Two commonly used symptom validity tests are the Test of Memory Malingering (TOMM) and Word Memory Test (WMT). After examining TOMM-WMT failure concordance rates, Green [Green, P. (2007). Making comparisons between forced-choice effort tests. In K. B. Boone (Ed.), Assessment of feigned cognitive impairment (pp. 50-77). New York: Guilford] urged widespread adoption of the WMT, arguing the TOMM is insensitive to feigned impairment. But Green (2007) used a skewed concordance method that favored WMT (one TOMM subtest vs. three WMT subtests). In the present study we compare pass/fail agreement rates with different combinations of TOMM and WMT subtests in 473 persons seeking compensation for predominately mild neurological trauma. We replicated Green (2007) using his asymmetrical method, but otherwise we found the WMT and TOMM produce comparable failure rates in samples at-risk for exaggeration with balanced comparison (three TOMM subtests vs. three WMT). Further work is necessary to compare WMT and TOMM specificities, as failure concordance designs establish reliability but are insufficient for proving validity.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.acn.2008.07.005 | DOI Listing |
J Infect
December 2024
German Center for Infection Research (DZIF), Partner site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany; Division of Clinical Infectious Diseases, Research Center Borstel, Parkallee 1-40, 23845 Borstel, Germany.
Objectives: Early detection of treatment failure is essential to improve the management of drug-resistant tuberculosis (DR-TB). We evaluated the molecular bacterial load assay (MBLA) in comparison to standard diagnostic tests for monitoring therapy of patients affected by drug-resistant TB.
Methods: The performance of MBLA in tracking treatment response in a prospective cohort of patients with pulmonary MDR/RR- and pre-XDR/XDR-TB was compared with mycobacterial culture, mycobacterial DNA detection using GeneXpert (Xpert) and microscopy detection of sputum acid-fast-bacilli.
J Mol Diagn
December 2024
Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Oxford Road, Manchester, M13 9WL; Division of Evolution, Infection and Genomics, School of Biological Sciences, University of Manchester, Manchester M13 9PT. Electronic address:
Pharmacogenetic guided prescribing can lead to more accurate medicine selection and dosing, improving patient outcomes and leading to better use of healthcare budgets. Loss of function (LoF) variants in CYP2C19 influence an individual's ability to metabolise clopidogrel, increasing the risk of secondary vascular events following ischemic stroke and percutaneous coronary intervention. In acute clinical contexts, centralized laboratory-based testing is too slow to inform timely clinical decision making.
View Article and Find Full Text PDFPerfusion
December 2024
Department of Pediatrics, Section of Pediatric Critical Care Medicine, Yale, New Haven, CT, USA.
Introduction: Extracorporeal membrane oxygenation (ECMO) provides critical support to patients in severe cardiac and respiratory failure, but it requires anticoagulation to prevent complications like bleeding and thrombosis. Heparin, the primary anticoagulant utilized, is monitored by activated partial thromboplastin time (aPTT) and anti-Factor Xa (AntiXa) levels. Discordance between the two assays complicates its titration and the impact on patient outcomes is not well-established.
View Article and Find Full Text PDFInt J Cardiol Congenit Heart Dis
March 2024
Surgical and Medical Cardiovascular Specialties Direction, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Background: Latin American registries of clinical and demographic profiles of ACHD are scarce. International guidelines classify disease complexity with different approaches. With these two regards, a registry was carried out to examine factors associated with mortality and to compare severity classifications in our population.
View Article and Find Full Text PDFInt J Surg
December 2024
Research Institute of General Surgery, Jinling Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Background: This study aimed to develop and validate a nomogram for predicting the presence of severe intra-abdominal adhesions before definitive surgery (DS) for anastomotic fistula following small intestine resection (SIR).
Methods: Patients were enrolled from January 2009 to October 2023 and were randomly divided (2:1) into development and validation cohorts. Predictors of severe adhesion were identified and integrated into a nomogram.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!