This study reports annual cyclic changes in the plasma levels of sex hormone binding globulin (SHBG), sex steroids (E(2), estradiol; T, testosterone; P, progesterone) and protein (PRT) in correlation with reproductive phases in both sexes of an Indian major carp, Labeo rohita. Plasma SHBG, E(2), T and PRT levels in females and SHBG and T levels in males showed steady increases (p<0.005) in parallel with the gonadosomatic index (GSI) escalation in the preparatory and prespawning phases attaining peak levels before spawning. During the late spawning and early postspawning phases, E(2), T and SHBG levels revealed an abrupt and significant descent coincident with the GSI in both the sexes. The plasma P levels in females, attaining measurable quantities only in prespawning phase, underwent a rapid increase followed by a quick decline to undetectable levels in the spawning phase. This occurrence of P for a short duration suggests a limited role in ovarian function. During the resting phase, the E(2), T and SHBG levels in both sexes declined to minimum in conjunction with a decrease in the GSI, while PRT showed an increase. These data suggest that a significant increase in SHBG (p<0.005) prior to spawning enhances its binding capacity with sex steroids in both sexes synchronizing the reproductive activity. The significant increase of PRT in females during early spawning reflects its role in oocyte function, while PRT and E(2) in males may not significantly affect the testicular activity.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.ygcen.2008.08.004 | DOI Listing |
Arch Dermatol Res
January 2025
Department of Plastic and Burn Surgery, West China Hospital, Sichuan University, No. 37, Guoxue Alley, Wuhou District, Chengdu, 610041, Sichuan Province, P. R. China.
Skin cancers continue to present unresolved challenges, particularly regarding the association with sex hormones, which remains a topic of controversy. A systematic review is currently warranted to address these issues. To analyze if sex hormones result in a higher incidence of skin cancers (cutaneous melanoma, basal cell carcinoma, squamous cell carcinoma).
View Article and Find Full Text PDFJ Steroid Biochem Mol Biol
January 2025
Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama 939-0398, Japan. Electronic address:
It is well known that vitamin D is essential for human health; however, many people suffer from vitamin D deficiency or insufficiency worldwide, including in Japan. Serum 25-hydroxyvitamin D (25(OH)D) concentrations are typically measured to evaluate vitamin D status. In a previous study, we demonstrated that the concentrations of vitamin D metabolites in urine, measured using the NLucVDR assay system composed of a split-type nanoluciferase and the ligand-binding domain (LBD) of the human vitamin D receptor, correlated with serum 25(OH)D concentrations measured using liquid chromatography-mass spectrometry (LC-MS) or electrochemiluminescence immunoassays (ECLIAs).
View Article and Find Full Text PDFAntimicrob Steward Healthc Epidemiol
August 2024
Department of Medicine, Hurley Medical Center, Flint, MI, USA.
Background: This cross-sectional study aims to determine the mortality trends in patients with SARS-CoV-2 infection during the pandemic in Flint, MI.
Methods: Records from 1,663 consecutive adult patients (≥18 years of age) with confirmed SARS-CoV-2 infection, admitted and discharged from our facility from 03/2020 through 02/2022, were abstracted and analyzed. Multivariable logistic regression analysis was performed to examine the association between study explanatory variables (ie, sex, age, co-morbidities, etc.
Environ Epidemiol
February 2025
Department of Public Health Sciences, University of Rochester Medical Center, Rochester, New York.
Background: Sex steroid hormones are critical for maintaining pregnancy and optimal fetal development. Air pollutants are potential endocrine disruptors that may disturb sex steroidogenesis during pregnancy, potentially leading to adverse health outcomes.
Methods: In the Environmental influences on Child Health Outcomes Understanding Pregnancy Signals and Infant Development pregnancy cohort (Rochester, NY), sex steroid concentrations were collected at study visits in early-, mid-, and late-pregnancy in 299 participants.
Arch Dermatol Res
January 2025
Department of Dermatology, Vanderbilt University Medical Center, Nashville, TN, USA.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!