A rapid and efficient one-pot method for the synthesis of quinazolinone derivatives and related heterocycles by condensation of 2-amino benzimidazole and 3-amino-1,2,4-triazole, as amine sources, with dimedone and different aldehydes in the presence of H6P2W18O(62).18H2O as a green and reusable catalyst in refluxing acetonitrile has been developed.
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http://dx.doi.org/10.1007/s11030-008-9086-8 | DOI Listing |
Clinics (Sao Paulo)
January 2025
Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address:
Objectives: It is estimated that up to 65 % of pwMS (people with multiple sclerosis) experience varying degrees of cognitive impairment, the most commonly affected domain being Information Processing Speed (IPS). As sleep disturbance is a predictor of detriments in IPS, the authors aimed to study the association between the severity of Restless Legs Syndrome (RLS) and Obstructive Sleep Apnea (OSA) symptoms with IPS in pwMS.
Methods: In a cross-sectional study, the authors enrolled people with relapsing-remitting and secondary progressive MS referred to the comprehensive MS center of Kashani Hospital in Isfahan, Iran.
Dis Colon Rectum
February 2025
Department of General Surgery, Jinling Medical School of Nanjing Medical University, Nanjing, China.
Background: Even in the biological era, permanent stoma is not uncommon in patients with Crohn's Disease.
Objective: This study aimed to investigate the incidence and risk factors of permanent stoma in Crohn's disease patients and provide clinical evidence for reducing this disabling outcome.
Design: Consecutive patients with Crohn's disease who underwent ostomies in the past decade were reviewed.
Inorg Chem
January 2025
Jiangxi Province Key Laboratory of Functional Organic Polymer, School of Chemistry and Materials Science, East China University of Technology, Nanchang 330013 Jiangxi, P. R. China.
The platelike nickel-terephthalate-type metal-organic framework nanoarrays (Ni-BDC NAs) on carbon cloth are obtained by employing agaric-like Ni(OH) NAs as sacrificial templates. The microenvironment of Ni-BDC NAs is modulated by various neighboring functional groups (-NH, -NO, and -Br) on the carboxylate ligand, exerting minimal destructive effects on the structure and morphology of Ni-BDC NAs. The electrochemical oxygen evolution reaction (OER) of Ni-BDC-NH NAs, Ni-BDC-NO NAs, and Ni-BDC-Br NAs exhibited a significant enhancement compared to that of Ni-BDC NAs alone, as evidenced by both experimental and theoretical assessments.
View Article and Find Full Text PDFAstrobiology
January 2025
Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA, USA.
We review the current state of understanding of Ceres as it relates to planetary protection policy for future landed missions, including for sample return, to the dwarf planet. The Dawn mission found Ceres to be an intriguing target for a mission, with evidence for the presence of regional, possibly extensive liquid at depth, and local expressions of recent and potentially ongoing activity. The Dawn mission also found a high abundance of carbon in the regolith, interpreted as a mix of carbonates and amorphous carbon, as well as locally high concentrations of organic matter.
View Article and Find Full Text PDFJ Am Chem Soc
January 2025
Department of Chemistry and Centre for Radiochemistry Research, The University of Manchester, Oxford Road, Manchester M13 9PL, U.K.
Although two examples of σ-bonded -bent [RSbSbR] (R = bulky organo- or Ga-groups) that formally contain the Sb radical trianion moiety are known in p-block chemistry, d- or f-element Sb radical trianion complexes, with or without R-substituents, have remained elusive. Here, we report that reduction of a 77:23 mix of [{Th(Tren)}(μ-η:η-Sb)] (, Tren = {N(CHCHNSiPr)}):[{Th(Tren)}(μ-SbH)] () with 1.5 equiv of KC in the presence of 1.
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