AI Article Synopsis
- Breast cancer affects 1 in 8 American women, and paclitaxel (Taxol) is a key treatment option for many of these patients.
- Hand surgeons may see unique complications related to taxane therapy, especially in the upper extremities.
- The text discusses a rare case of a felon (a severe finger infection) occurring in a breast cancer patient undergoing paclitaxel treatment, highlighting it as a more severe form of drug-related nail issues.
Article Abstract
Breast cancer now affects 1 in 8 American women and the taxane agent paclitaxel (Taxol Bristol-Myers Squibb) is a major tool in the treatment of many such patients. Hand surgeons are therefore likely to encounter upper extremity complications related to the use of taxane therapy. We present an unusual case of a felon developing in a breast cancer patient on paclitaxel therapy with no antecedent history of trauma. Whereas onycholysis and subungual hemorrhage are reported complications of taxane therapy (Fig. 1), an acute felon with or without associated paronychia is an unusual and more aggressive manifestation of this drug-related nail dystrophy.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527140 | PMC |
| http://dx.doi.org/10.1007/s11552-007-9029-3 | DOI Listing |
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