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Prevalence and Correlates of the Concurrence of Autism Spectrum Disorder and Obsessive Compulsive Disorder in Children and Adolescents: A Systematic Review and Meta-Analysis.
Brain Sci
April 2024
Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London WC2R 2LS, UK.
Background: Autism spectrum disorder (ASD) and obsessive compulsive disorder (OCD) are two common and impairing neurodevelopmental conditions with partial symptomatic overlap. The aim of this study is to systematically and meta-analytically examine the following: (i) the prevalence of an OCD diagnosis among young people with ASD, (ii) the prevalence of an ASD diagnosis among young people with OCD, and (iii) the clinical and therapeutic implications of such comorbidity.
Method: A multistep literature search was performed from database inception until 17 November 2023.
Craving and emotional responses to trauma and cannabis cues in trauma-exposed cannabis users: Influence of PTSD symptom severity.
Addict Behav
February 2022
Dalhousie University, Department of Psychology and Neuroscience, Life Sciences Centre, 1355 Oxford Street, PO Box 15000, B3H 4J1 Halifax, Nova Scotia, Canada; Dalhousie University, Department of Psychiatry, 5909 Veterans' Memorial Lane, 8th Floor, Abbie J. Lane Memorial Building, QEII Health Sciences Centre, B3H 2E2 Halifax, Nova Scotia, Canada.
Conditioned craving to trauma cues and avoidance learning have both been implicated in the high concurrence of trauma-related distress and substance misuse. Using a cue-exposure paradigm involving personalized trauma, cannabis, and neutral cues, we examined if conditioned craving and/or elevated negative affect to trauma cues are mechanisms linking PTSD and cannabis use disorder. Fifty-one trauma-exposed cannabis users were randomly presented the three cue types.
View Article and Find Full Text PDFAbnormalities of Localized Connectivity in Obsessive-Compulsive Disorder: A Voxel-Wise Meta-Analysis.
Front Hum Neurosci
September 2021
Nursing Department, West China Second University Hospital, Sichuan University, Chengdu, China.
A large amount of resting-state functional magnetic resonance imaging (rs-fMRI) studies have revealed abnormalities of regional homogeneity (ReHo, an index of localized intraregional connectivity) in the obsessive-compulsive disorder (OCD) in the past few decades, However, the findings of these ReHo studies have remained inconsistent. Hence, we performed a meta-analysis to investigate the concurrence across ReHo studies for clarifying the most consistent localized connectivity underpinning this disorder. A systematic review of online databases was conducted for whole-brain rs-fMRI studies comparing ReHo between OCD patients and healthy control subjects (HCS).
View Article and Find Full Text PDFUnderlying Mechanism of the Comorbid Presence of Buying Disorder with Gambling Disorder: A Pathways Analysis.
J Gambl Stud
March 2019
Ciber Fisiopatología Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Barcelona, Spain.
Buying disorder (BD) and gambling disorder (GD) are behavioral addictions that are increasingly being researched and treated by mental health professionals. This study analyzes the underlying mechanisms of the comorbidity between both conditions in a sample of treatment-seeking patients. The sample included n = 127 patients recruited from a specialized unit in addictive behaviors at a public university hospital who presented BD symptoms with and without GD.
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