We report herein an efficient and simple route to synthesize 1-nosyl 3,3-dichloro-beta-lactams using a Staudinger reaction between N-nosyl imines and dichloroketene. The resulting dichloroazetidines were opened to afford highly functionalized building blocks.
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| http://dx.doi.org/10.1021/jo8014193 | DOI Listing |
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