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Validation of an improved reference freeze-dried direct agglutination test for detecting leishmaniasis in the canine reservoir.
Access Microbiol
January 2025
Department of Medical Laboratory Science, Faculty of Medical and Health Sciences, Liwa College, Abu Dhabi, UAE.
Proper identification and management of post-kala-azar dermal leishmaniasis (PKDL) and canine leishmaniasis (CanL) cases are among the prerequisites to the effective control of visceral leishmaniasis worldwide. Unlike PKDL, CanL still awaits effective improvement because of its cryptic nature, absence of parasites in lesions or lymph nodes and not complete sensitivity of some diagnostic tools in use. Because of the need for certain skills and equipment, both the liquid direct agglutination test and freeze-dried direct agglutination test (FD-DAT) versions are, in comparison with the indirect immunofluorescence antibody test (IFAT) or enzyme-linked immunosorbent assay (ELISA), practical and feasible diagnostic alternatives.
View Article and Find Full Text PDFChallenges and strategies for improving medication adherence among adolescent psychiatric patients: A qualitative study.
Glob Ment Health (Camb)
December 2024
Centre for Community Health Studies (ReaCH), Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Despite significant advancements in the development of psychotropic medications, increasing adherence rates remain a challenge in the treatment and management of psychiatric disorders. The purpose of this study is to qualitatively explore the challenges underlying medication adherence and strategies to improve it among adolescents with psychiatric disorders in Malaysia. This qualitative research design presents results from 17 semi-structured interviews with adolescent psychiatric patients, aged 11 to 19 years old, from public hospitals across Peninsular Malaysia.
View Article and Find Full Text PDFPathways to care for psychosis in rural Uganda: Mixed-methods study of individuals with psychosis, family members, and local leaders.
Glob Ment Health (Camb)
January 2025
Department of Psychiatry Mbarara University of Science and Technology, Mbarara, Uganda.
Background: Low- and middle-income countries (LMICs) bear a disproportionate burden of mental illness, with limited access to biomedical care. This study examined pathways to care for psychosis in rural Uganda, exploring factors influencing treatment choices.
Methods: We conducted a mixed-methods study in Buyende District, Uganda, involving 67 in-depth interviews and 4 focus group discussions (data collection continued until thematic saturation was reached) with individuals with psychotic disorders, family members, and local leaders.
Cultural adaptation of an evidence-based intervention to address mental health among youth affected by armed conflict in Colombia: An application of the ADAPT-ITT approach and FRAME-IS reporting protocols.
Glob Ment Health (Camb)
November 2024
Boston College, School of Social Work, Chestnut Hill, MA, USA.
Background: In Colombia, over 9 million people have been impacted by armed conflict, creating a significant need for mental health services. This study aimed to culturally adapt and pilot test the Youth Readiness Intervention (YRI), an evidence-based transdiagnostic mental health intervention, for conflict-affected Colombian youth aged 18-28 years.
Methods: The eight phases of the Assessment, Decision, Administration, Production, Topical Experts, Integration, Training, and Testing (ADAPT-ITT) framework were used to culturally adapt the YRI for conflict-affected Colombian youth.
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