Comparison of self-gated cine MRI retrospective cardiac synchronization algorithms.

J Magn Reson Imaging

Department of Electrical Engineering and Computer Science, Northwestern University, Evanston, Illinois 60208, USA.

Published: September 2008

Purpose: To determine whether improved self-gating (SG) algorithms can provide superior synchronization accuracy for retrospectively gated cine MRI.

Materials And Methods: First difference, template matching, and polynomial fitting algorithms were implemented to improve the synchronization of MRI data using cardiac SG signals. Cine datasets were acquired during short-axis, two-, three-, and four-chamber cardiac MRI scans. The root-mean-square (RMS) error of SG synchronization positions compared to detected R-wave positions were calculated along with the mean square error (MSE) and peak signal-to-noise ratio (PSNR) comparing SG to electrocardiogram (ECG)-gated images. Overall image quality was also compared by two expert reviewers.

Results: RMS errors were highest for the first difference method for all orientations. Improvements for both template matching and cubic polynomial fitting methods were significant for two-, three-, and four-chamber scans. MSE values were lower and PSNR were significantly higher for the cubic method compared to the first difference method for all orientations. Reviewers scored the images to be of comparable quality.

Conclusion: Template matching and polynomial fitting improved the accuracy of cardiac cycle synchronization for two-, three-, and four-chamber scans; improvements in SG synchronization accuracy were reflected in improvements in analytical image quality. Implementation of robust postprocessing algorithms may bring SG approaches closer to clinical utilization.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597286PMC
http://dx.doi.org/10.1002/jmri.21514DOI Listing

Publication Analysis

Top Keywords

template matching
12
polynomial fitting
12
two- three-
12
three- four-chamber
12
synchronization accuracy
8
matching polynomial
8
image quality
8
difference method
8
method orientations
8
four-chamber scans
8

Similar Publications

Background: Quantitative Susceptibility Mapping (QSM) offers significant potential for studying metal and iron homeostasis in the brain and serves as a diagnostic tool for various pathologies, such as Alzheimer's disease. However, the precision of QSM spatial normalization for older adults depends on the quality and representativeness of the chosen template and the type of information used during image registration. This study compares three available QSM templates in terms of their representativeness and precision of inter-subject matching for older adult QSM data.

View Article and Find Full Text PDF

Background: Dementia with Lewy bodies (DLB) frequently co-occurs with Alzheimer's disease (AD) pathologies, exacerbating disease progression. Biophysical models of diffusion imaging data, such as Neurite Orientation Dispersion and Density Imaging (NODDI), may reveal novel insights into the neurobiological substrates of AD on cortical and white matter microstructural injury.

Method: A cohort of 57 DLB patients on the DLB spectrum (33 clinically probable DLB and 14 prodromal DLB) and 57 cognitively unimpaired (CU) controls underwent NODDI and PET imaging with [F]-Flortaucipir and [C]-PiB (Table 1).

View Article and Find Full Text PDF

Background: White matter hyperintensities (WMHs) are age-related radiological abnormalities indicative of small vessel disease. It is unclear if WMHs in different regions represent similar pathophysiology and etiology. Here, we developed a framework to estimate WMH pathophysiology in vivo, which allowed us to precisely characterize spatial patterns of WMH tissue alterations associated with four disorders.

View Article and Find Full Text PDF

Background: Alzheimer's disease (AD) is an heterogenous disorder characterized by the accumulation of amyloid-beta (Aβ) and tau. One possible explanation for the clinical and pathological variation in AD lies in the presence of distinct conformational strains of Aβ. Numerous studies provide compelling evidence for the existence of such strains as well as their ability to template their conformations in a prion-like manner.

View Article and Find Full Text PDF

Background: White matter hyperintensities (WMHs) are age-related radiological abnormalities indicative of small vessel disease. It is unclear if WMHs in different regions represent similar pathophysiology and etiology. Here, we developed a framework to estimate WMH pathophysiology in vivo, which allowed us to precisely characterize spatial patterns of WMH tissue alterations associated with four disorders.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!