A pathogenic strain of infectious bursal disease virus has been purified by density gradient centrifugation, principally on sucrose and tartrate gradients. Examination of gradient peak fractions by electron microscopy has revealed two populations of particles of average size 62 nm and 20 nm, which band together on sucrose and tartrate gradients. Purified virus has been shown to reproduce the typical symptoms and lesions of infectious bursal disease. The possible classification of the larger virus particle in the diplornavirus group and the origin of the smaller particle are discussed.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/03079457509353864 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Structure of the T=13 capsid of infectious pancreatic necrosis virus (IPNV)-a salmonid birnavirus.
J Virol
January 2025
Laboratory of Molecular Biophysics, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.
Birnaviruses infect a broad range of vertebrate hosts, including fish and birds, and cause substantial economic losses in the fishery and livestock industries. The infectious pancreatic necrosis virus (IPNV), an aquabirnavirus, specifically infects salmonids. While structures on T=1 subviral particles of the birnaviruses, including IPNV, have been studied, structural insights into the infectious T=13 particles have been limited to the infectious bursal disease virus (IBDV), an avibirnavirus.
View Article and Find Full Text PDFSevere pertussis infections in pediatric intensive care units: a multicenter study.
Eur J Pediatr
January 2025
Department of Biostatistics and Medical Informatics, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey.
Unlabelled: This study aims to evaluate the clinical course of critical pertussis illness to the pediatric intensive care unit in Istanbul. The study was conducted as a multicenter, retrospective study between January 1, 2023, and December 31, 2023. Cases with positive polymerase chain reaction testing for Bordetella pertussis of nasopharyngeal swab samples within the first 24 h of pediatric intensive care unit admission were recorded.
View Article and Find Full Text PDFSuccessful Treatment of Adventitious Bursitis With Marginal Resection in a 23-Year-Old Patient: A Case Report.
Cureus
December 2024
Department of Orthopedics and Traumatology, Cerrahpasa Faculty of Medicine, Istanbul University - Cerrahpasa, Istanbul, TUR.
Adventitious bursitis is an inflammatory condition affecting bursae. Distinct from primary or infectious bursitis, adventitious bursitis typically develops secondary to conditions such as rheumatoid arthritis, gout, or repetitive joint overuse. The resulting inflammation can lead to pain, swelling, and restricted mobility, significantly impacting patients' quality of life.
View Article and Find Full Text PDFA Unique Cause of Chronic Right Hip Pain and Unilateral Leg Swelling 10 Years Following Total Hip Arthroplasty.
Am J Phys Med Rehabil
November 2024
Department of Physical Medicine & Rehabilitation, University of Minnesota, Minneapolis, Minnesota.
Patient is a 64-year-old female with a history of right total hip arthroplasty (THA) who presented with progressive painful right lower extremity edema and chronic groin pain for 2 years. A CT scan from October 2021 revealed an expanding, large iliopsoas bursal fluid collection that caused compression of the right common femoral artery and vein in June 2023. Further workup excluded deep venous thrombosis or infectious causes.
View Article and Find Full Text PDFOne-Step Multiplex Real-Time Fluorescent Quantitative Reverse Transcription PCR for Simultaneous Detection of Four Waterfowl Viruses.
Microorganisms
November 2024
Guangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, College of Animal Science and Technology, Guangxi Grass Station, Guangxi University, Nanning 530004, China.
Duck Tembusu virus (DTMUV), duck hepatitis virus (DHV), Muscovy duck reovirus (MDRV), and Muscovy duck parvovirus (MDPV) represent four emergent infectious diseases impacting waterfowl, which can be challenging to differentiate due to overlapping clinical signs. In response to this, we have developed a one-step multiplex real-time fluorescence quantitative reverse transcription PCR (qRT-PCR) assay, capable of simultaneously detecting DTMUV, DHV, MDRV, and MDPV. This method exhibits high specificity, avoiding cross-reactivity with other viruses such as Fowl adenoviruses (FADV), infectious bursal disease virus (IBDV), infectious bronchitis virus (IBV), infectious laryngotracheitis virus (ILTV), Haemophilus paragallinarum (Hpg), duck circovirus (DUCV), goose astrovirus (GoAstV), and mycoplasma gallisepticum (MG).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!