Synthesis and antiviral evaluation of 7-fluoro-7-deaza-2-aminopurine nucleoside derivatives.

Nucleic Acids Symp Ser (Oxf)

Idenix Pharmaceuticals, Medicinal Chemistry Laboratory, Cap Gamma, 1682 Rue de la Valsière, 34189 Montpellier Cedex 4, France.

Published: November 2010

Three 7-fluoro-7-deaza-2-aminopurine nucleoside derivatives were synthesized and evaluated as potential inhibitors of RNA virus replication, including hepatitis C virus (HCV).

Download full-text PDF

Source
http://dx.doi.org/10.1093/nass/nrn301DOI Listing

Publication Analysis

Top Keywords

7-fluoro-7-deaza-2-aminopurine nucleoside
8
nucleoside derivatives
8
synthesis antiviral
4
antiviral evaluation
4
evaluation 7-fluoro-7-deaza-2-aminopurine
4
derivatives three
4
three 7-fluoro-7-deaza-2-aminopurine
4
derivatives synthesized
4
synthesized evaluated
4
evaluated potential
4

Similar Publications

Synthesis and antiviral evaluation of 7-fluoro-7-deaza-2-aminopurine nucleoside derivatives.

Nucleic Acids Symp Ser (Oxf)

November 2010

Idenix Pharmaceuticals, Medicinal Chemistry Laboratory, Cap Gamma, 1682 Rue de la Valsière, 34189 Montpellier Cedex 4, France.

Three 7-fluoro-7-deaza-2-aminopurine nucleoside derivatives were synthesized and evaluated as potential inhibitors of RNA virus replication, including hepatitis C virus (HCV).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!