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[Reversible central pontine myelinolysis without hyponatremia in a child with acute lymphoblastic leukemia: a case report].
Pan Afr Med J
May 2023
Unité d'Oncologie Pédiatrique, Service de Pédiatrie, Hôpital Mère-Enfant Centre Hospitalier Universitaire Hassan II, Fès, Maroc.
Central pontine myelinolysis is a demyelinating disorder mainly affecting the central pons. In some cases, it is associated with extrapontine myelinolysis. It is usually caused by rapid correction of hyponatremia and osmotic shock.
View Article and Find Full Text PDF[Osmotic demyelination syndrome complicating the quick correction of a severe hyponatremia associated with hypokalemia].
Pan Afr Med J
August 2020
Service d'Accueil des Urgences Vitales, Département d'Anesthésie Réanimation et Urgences, Hôpital Ibn Tofail, CHU Mohammed VI, Faculté de Médecine et de Pharmacie de Marrakech, Université Cadi Ayyad, Marrakech, Maroc.
Osmotic demyelination syndrome is characterized by the loss of myelin in the center of the basis pontis and other areas of the central nervous system. We report a case of osmotic demyelination syndrome in a 55-year-old female, with a past medical history of arterial hypertension and multi-level cervical spondylosis, hospitalized for acute altered mental status complicating an array of acute gastroenteritis, the patient was afebrile. The course was marked by neurologic aggravation with confusion, aphasia, tetraplegia and osteo-tendinous areflexia.
View Article and Find Full Text PDF[Hyponatremia, alcohol and ataxia].
Rev Med Interne
February 2016
Service de médecine interne, hôpital Ambroise-Paré, AP-HP, 9, avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France; UFR des sciences de la santé, université Versailles Saint-Quentin-en-Yvelines, 55, avenue de Paris, 78000 Versailles, France.
Central pontine and extra-pontine myelinolysis (CPM/EPM) is a rare neurological disorder, well documented for more than 50 years but whose pathogenesis remains obscure. The existence of predisposing factors occurs in the most cases; chronic alcohol abuse is one of the most commonly encountered, among many others. Alcohol withdrawal represents an additional vulnerability factor, being responsible for electrolyte imbalances which are not always demonstrable but are certainly involved in the development of CPM and/or EPM.
View Article and Find Full Text PDF[Centropontine myelinosis in a child undergoing chemotherapy].
Arch Pediatr
December 2013
Service de radiopédiatrie de l'Hôpital d'enfants Béchir Hamza, université de Tunis El Manar, Tunis, Tunisie.
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