Objective: Our goal was to report a case of malignant neuroleptic syndrome in a patient administered with both oxcarbazepine (OXCBZ) and amisulpride (AM).
Method: We present a case of a young man who presented with symptoms of malignant neuroleptic syndrome after progressive titration of OXCBZ (1,200 mg) added to the long-term treatment with AM (800 mg).
Results: After discontinuation of AM and administration of dopaminergic drugs, his clinical symptoms improved gradually.
Conclusion: This case suggests that clinicians should consider the risk of neuroleptic malignant syndrome when OXCBZ is coadministered to patients undergoing long-term treatment with neuroleptics.
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| http://dx.doi.org/10.1016/j.genhosppsych.2008.03.007 | DOI Listing |
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