Both flow and image cytometry have routine, reliable methods for ploidy analysis, each with its dbacks. LSC offers a non-destructive and non-consumptive method of analysis that allows repeated sample analysis as well as storage for later re-evaluation. Owing to the extremely small sample requirement, specimens can be obtained through minimally invasive procedures such as fine-needle aspirate biopsies or simple swabs. Tumors located at sites unsuitable for routine biopsy can be analyzed even on an out-patient basis.

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http://dx.doi.org/10.1002/0471142956.cy0720s22DOI Listing

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