Synthesis of molecular nanocages by click chemistry.

J Org Chem

Instituto de Biotecnología, Departamento de Química Orgánica, Facultad de Ciencias, Campus Fuentenueva s/n, Universidad de Granada, Granada E-18071, Spain.

Published: October 2008

AI Article Synopsis

  • The text discusses the efficient creation of nanosized cage compounds using a method called "click chemistry."
  • This process involves a chemical reaction between polyalkyne and polyazide derivatives, facilitated by a specific catalyst, Cu(I).
  • The reaction produces high yields of the desired compounds, highlighting the effectiveness of this approach in synthetic chemistry.

Article Abstract

The covalent synthesis of nanosized cage compounds is easily performed in high yields using "click chemistry" methodology through the Cu(I)-catalyzed ligation of adequate polyalkyne and polyazide derivatives using (EtO)3P x CuI as catalyst.

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Source
http://dx.doi.org/10.1021/jo801324xDOI Listing

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