We present a new analysis of the helicity parton distributions of the nucleon. The analysis takes into account the available data from inclusive and semi-inclusive polarized deep inelastic scattering, as well as from polarized proton-proton (p-p) scattering at RHIC. For the first time, all theoretical calculations are performed fully at next-to-leading order (NLO) of perturbative QCD, using a method that allows incorporation of the NLO corrections in a very fast and efficient way in the analysis. We find evidence for a rather small gluon polarization in the nucleon, over a limited region of momentum fraction, and for interesting flavor patterns in the polarized sea.
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http://dx.doi.org/10.1103/PhysRevLett.101.072001 | DOI Listing |
Protein Sci
February 2025
Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada.
Polymyxins are last-resort antimicrobial peptides administered clinically against multi-drug resistant bacteria, specifically in the case of Gram-negative species. However, an increasing number of these pathogens employ a defense strategy that involves a relay of enzymes encoded by the pmrE (ugd) loci and the arnBCDTEF operon. The pathway modifies the lipid-A component of the outer membrane (OM) lipopolysaccharide (LPS) by adding a 4-amino-4-deoxy-l-arabinose (L-Ara4N) headgroup, which renders polymyxins ineffective.
View Article and Find Full Text PDFUltrason Sonochem
January 2025
School of Traditional Chinese Medicine and Food Engineering, Shanxi Provincial Key Laboratory of Traditional Chinese Medicine Processing, Shanxi University of Chinese Medicine, Jinzhong 030619, PR China. Electronic address:
Polysaccharides from the dried tuber of Typhonium giganteum Engl. (TGEPs) were obtained by utilizing ultrasonic-assisted extraction (UAE) as the extraction method. The determination of optimal process parameters for the UAE of TGEPs (TGEP-U) was accomplished through the application of response surface methodology (RSM).
View Article and Find Full Text PDFBiomolecules
January 2025
Department of Medical Biology, Faculty of Medicine, Recep Tayyip Erdogan University, Rize 53020, Türkiye.
The innate immune response serves as the primary defense against viral infections, with the recognition of viral nucleic acids by pattern recognition receptors (PRRs) initiating antiviral responses. Mitochondrial antiviral-signaling protein (MAVS) acts as a pivotal adaptor protein in the RIG-I pathway. Alternative splicing further diversifies MAVS isoforms.
View Article and Find Full Text PDFBiology (Basel)
December 2024
Graduate School of Science and Technology, Niigata University, 8050 Ikarashi 2 No-Cho, Nishi-ku, Niigata 950-2181, Japan.
Public acceptance of genetically modified crops engineered with (Bt) insecticidal protein genes (BT-GMCs), which confer resistance to various lepidopteran insect pests, is generally lacking. As a major concern over BT-GMCs is the allergenicity of insecticidal proteins, alleviating safety concerns should help increase public acceptance. In this study, three lepidopteran-specific Bt toxins, Cry1Aa, Cy1Ab, and Cry1Ac, were treated with simulated digestive fluids under various conditions.
View Article and Find Full Text PDFJ Neurosurg Spine
January 2025
2Cleveland Clinic Center for Spine Health, Cleveland Clinic, Cleveland; and.
Objective: Spinal fusion is a commonly performed surgical procedure used to relieve pain, deformity, and instability of various spinal pathologies. Although there have been attempts to standardize spinal fusion assessment radiologically, there is currently no unified definition that also considers clinical symptomology. This review attempts to create a more holistic and standardized definition of spinal fusion.
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