Influence of pineal peptides on the dynamics of the circadian and minute motor biorhythms in rats.

Neurosci Behav Physiol

Department of the Pharmacology of the Vestibular Apparatus, State Medical Institute, Stavropol.

Published: September 1991

A peptide preparation of the pineal, epithalamin, when administered chronically, exerts a modulating influence on the diurnal fluctuations of the motoric activity of rats. It also decreases the amplitude of apomorphine stereotypy and induces a restructuring of a modulatory character in its rhythmic structure. It is hypothesized that the pineal peptides participate in the maintenance of homeostasis by means of the stabilization of rhythmic processes of various periods.

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http://dx.doi.org/10.1007/BF01182890DOI Listing

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