Prenatal diagnosis of juvenile granulosa cell tumor of the testis.

J Pediatr Urol

Doernbecher Children's Hospital, Oregon Health and Science University, Division of Urology, Department of Surgery, 3303 Southwest Bond Avenue, 10th Floor, Portland, OR 97239, USA.

Published: December 2008

AI Article Synopsis

  • Juvenile granulosa cell tumor is a rare benign tumor found in the testicular stroma, representing 1-5% of tumors in boys before puberty.
  • Previous studies have identified such tumors on prenatal ultrasounds, indicating their potential for early detection.
  • The report discusses a specific case where a testis tumor diagnosed before birth was confirmed to be a juvenile granulosa cell tumor after further examination.

Article Abstract

Juvenile granulosa cell tumor is a rare benign neoplasm of the testicular stroma that accounts for 1-5% of all prepubertal testis tumors [Metcalfe PD, Farivar-Mohseni H, Farhat W, McLorie G, Khoury A, Bagli DJ. Pediatric testicular tumors: contemporary incidence and efficacy of testicular preserving surgery. J Urol 2003;170:2412-2416; Ross JH, Rybicki L, Kay R. Clinical behavior and a contemporary management algorithm for prepubertal testis tumors: a summary of the prepubertal testis tumor registry. J Urol 2002;168:1675-1679]. A prior case series retrospectively identified a cystic testis tumor on prenatal ultrasound images which was subsequently diagnosed as a juvenile granulosa cell tumor [Bryan DE, Cain MP, Casale AJ. Juvenile granulosa-theca cell (sex cord-stromal) tumor of the infant testis. J Urol 2003;169:1497-1498]. We report a case of a prenatally diagnosed testis tumor which was subsequently diagnosed as a juvenile granulosa cell tumor.

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http://dx.doi.org/10.1016/j.jpurol.2008.04.005DOI Listing

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