Congenital adrenal hyperplasia causing clitoromegaly.

J Coll Physicians Surg Pak

Department of Obstetrics and Gynaecology, Baqai Medical University, Karachi.

Published: June 2008

Congenital Adrenal Hyperplasia (CAH) is caused by congenital insufficiency of the enzyme 21 - hydroxylase (21-OHD) in the cortisol synthesis pathway. Because of the virilizing effects of androgens over-production, affected girls develop clitoral hypertrophy. Three patients with CAH are discussed below along with their surgical management and follow-up.

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