Modern aberrometry measures standard and so-called higher-order refractory aberrations. Ophthalmology and optometry use Zernike polynomials to describe aberrations of the retina and lens causing refractory errors. Aberrations of a higher order sometimes follow successful laser surgery, causing reduced vision and inducing patient dissatisfaction; enhanced wavefront data can help to avoid this. Aberrometry is used also for objective measurement of refractory changes. Wavefront techniques and their clinical application enable many options for understanding the delicate balance of eye optics. The future of refractive surgery lies in increasingly individualized treatment to suppress higher degrees of aberration and thus improve clinical results. Patients will continue placing greater demand on individualized intraocular lenses that correct higher-order aberrations.
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http://dx.doi.org/10.1007/s00347-008-1822-z | DOI Listing |
Sci Rep
January 2025
Department of Physics, University of Trieste, 34127, Trieste, Italy.
Phase-contrast micro-tomography ([Formula: see text]CT) with synchrotron radiation can aid in the differentiation of subtle density variations in weakly absorbing soft tissue specimens. Modulation-based imaging (MBI) extracts phase information from the distortion of reference patterns, generated by periodic or randomly structured wavefront markers (e.g.
View Article and Find Full Text PDFSci Rep
January 2025
Japan Agency for Marine-Earth Science and Technology, 3173-25, Showa-machi, Kanazawa-ku, Yokohama, Kanagawa, 2360001, Japan.
Subsurface seismic velocity structure is essential for earthquake source studies, including hypocenter determination. Conventional hypocenter determination methods ignore the inherent uncertainty in seismic velocity structure models, and the impact of this oversight has not been thoroughly investigated. Here, we address this issue by employing a physics-informed deep learning (PIDL) approach that quantifies uncertainty in two-dimensional seismic velocity structure modeling and its propagation to hypocenter determination by introducing neural network ensembles trained on active seismic survey data, earthquake observation data, and the physical equation of wavefront movement.
View Article and Find Full Text PDFVestn Oftalmol
December 2024
Krasnov Research Institute of Eye Diseases, Moscow, Russia.
Purpose: This study compares the functional outcomes of correction using two different types of aberrational extended depth-of-focus (EDOF) intraocular lenses (IOLs).
Material And Methods: The study was conducted in two standardized groups (20 patients, 20 eyes in each group). Patients in group 1 were implanted EDOF IOL I, in group 2 - EDOF IOL II.
Dev Biol
December 2024
Stowers Institute for Medical Research, USA; Children's Mercy Hospital/Children's Mercy Research Institute, USA. Electronic address:
A core framework of the gene regulatory network (GRN) governing neural crest (NC) cell development has been generated by integrating separate inputs from diverse model organisms rather than direct comparison. This has limited insights into the diversity of genes in the NC cell GRN and extent of conservation of newly identified transcriptional signatures in cell differentiation and invasion. Here, we address this by leveraging the strengths and accessibility of the avian embryo to precise developmental staging by egg incubation and use an integrated analysis of chick (HH13) and mouse (E9.
View Article and Find Full Text PDFJ Synchrotron Radiat
January 2025
LCLS, SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, CA 94025, USA.
Time-domain modeling of the thermal deformation of crystal optics can help define acceptable operational ranges across the pulse-energy repetition-rate phase space. In this paper, we have studied the transient thermal deformation of a water-cooled diamond crystal for a cavity-based X-ray free-electron laser (CBXFEL), either an X-ray free-electron laser oscillator (XFELO) or a regenerative amplifier X-ray free-electron laser (RAFEL), by numerical simulations including finite-element analysis and advanced data processing. Pulse-by-pulse transient thermal deformation of a 50 µm-thick diamond crystal has been performed with X-ray pulse repetition rates between 50 kHz and 1 MHz.
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