Target-driven selection in a dynamic nitrone library.

Chem Commun (Camb)

EaStCHEM and Centre for Biomolecular Sciences, School of Chemistry, University of St Andrews, St Andrews, Fife, UK KY16 9ST.

Published: September 2008

Nitrones undergo dynamic exchange in chloroform at room temperature through two mechanisms-hydrolysis and recombination or hydroxylamine addition/elimination; this dynamic exchange is harnessed to select a nitrone-based bis(amidopyridine) receptor for diacids from a group of four nitrones through its binding to a glutaric acid-based target.

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Source
http://dx.doi.org/10.1039/b805945dDOI Listing

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