Priorities and uncertainties of administering chemotherapy in a pregnant woman with newly diagnosed colorectal cancer.

J Oncol Pharm Pract

Mary Babb Randolph Cancer Center, Section of Hematology/Oncology, Department of Medicine, West Virginia University, Morgantown, WV 26506, USA.

Published: March 2009

Background: The absence of treatment standards for the use of chemotherapy in pregnancy is due, in part, to the fact that cancer in the gravid female is relatively uncommon.

Method: A case (of a pregnant woman with newly diagnosed colorectal cancer) is presented to explore this area of medical uncertainty.

Result: Managed by a multi-disciplinary team, successful prolongation of gestation was achieved with an oxaliplatin-based chemotherapy regimen.

Conclusion: A perspective of the ongoing conflict between prolonging the mother's life and preserving fetal development is highlighted. Although not life-saving, administration of chemotherapy in this woman was life-sparing.

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http://dx.doi.org/10.1177/1078155208094101DOI Listing

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