Background: The absence of treatment standards for the use of chemotherapy in pregnancy is due, in part, to the fact that cancer in the gravid female is relatively uncommon.
Method: A case (of a pregnant woman with newly diagnosed colorectal cancer) is presented to explore this area of medical uncertainty.
Result: Managed by a multi-disciplinary team, successful prolongation of gestation was achieved with an oxaliplatin-based chemotherapy regimen.
Conclusion: A perspective of the ongoing conflict between prolonging the mother's life and preserving fetal development is highlighted. Although not life-saving, administration of chemotherapy in this woman was life-sparing.
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http://dx.doi.org/10.1177/1078155208094101 | DOI Listing |
J Midwifery Womens Health
January 2025
Sexual Health and Reproductive Equity Program, School of Social Welfare, University of California, Berkeley, California.
As access to doula services expands through state Medicaid coverage and specific initiatives aimed at improving maternal health equity, there is a need to build and improve upon relationships between the doula community, hospital leaders, and clinical staff. Previous research and reports suggest rapport-building, provider education, and forming partnerships between community-based organizations and hospitals can improve such relationships. However, few interventions or programs incorporating such approaches are described in the literature.
View Article and Find Full Text PDFRev Gastroenterol Peru
January 2025
Department of Pathology, Santa Casa Hospital, Porto Alegre, Brazil.
Pancreatic ductal adenocarcinoma during pregnancy is extremely rare. Overall, including our case, only 19 cases confirmed antepartum have been reported to date. We report the case of a 37 year-old woman at 24 weeks of pregnancy in whom a pancreatic adenocarcinoma was identified during investigation of a suspected acute pancreatitis.
View Article and Find Full Text PDFInt J Gynaecol Obstet
January 2025
Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Pulmonary sequestration is a rare pulmonary malformation, typically characterized by asymptomatic presentation or recurrent pulmonary infections, with chest pain and hemothorax being exceedingly rare occurrences. The rupture and hemorrhage of maternal pulmonary sequestration during pregnancy pose a life-threatening condition that is challenging to diagnose. We present a case of a 37-year-old pregnant woman in her third trimester who presented with acute progressive hemothorax, a complication arising from maternal pulmonary sequestration.
View Article and Find Full Text PDFInt J Gynaecol Obstet
January 2025
Endocrinology Division-Department of Medicine, University of Puerto Rico, San Juan, Puerto Rico, USA.
There is limited research concerning the transgender population's health issues, such as gender dysphoria, and disparities within the healthcare system, especially in the Latino or Hispanic population. This study aimed to report the case of a Puerto Rican transgender man who achieved pregnancy without reproductive assistance after cessation of testosterone therapy for 3 months and who in the postpartum period experienced significant gender dysphoria. A narrative literature review was carried out to identify the role of gender dysphoria in pregnancy, lactation, health-related spaces, and mental health.
View Article and Find Full Text PDFBMC Pregnancy Childbirth
January 2025
Oregon Health & Science University-Portland State University School of Public Health, Portland, OR, USA.
Background: Understanding the risks and effects of gestational weight gain (GWG) is a prominent area of perinatal research but approaches for quantifying GWG are evolving and remain underdeveloped, especially in clinical settings for underserved demographic subgroups. To fill this gap, we demonstrated and compared six GWG metrics across pre-pregnancy BMI classifications: total GWG, trimester-specific linear rate of GWG, adherence to total and trimester-specific recommendations, area under the curve, and GWG for gestational age z-scores.
Methods: We used clinical data on 44,801 pregnant people from community-based health care organizations with extensive longitudinal measures and substantial representation of understudied subgroups.
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