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Prevalence of congenital and acquired toxoplasmic uveitis as evidenced by two serologic methods. | LitMetric

AI Article Synopsis

  • A study examined the presence of anti-Toxoplasma antibodies in 34 patients with uveitis and 20 healthy controls, revealing a 26.5% overall positive rate.
  • The prevalence of antibodies was significantly higher in patients with posterior uveitis (42.9%) compared to anterior uveitis (7.1%) and healthy controls (10%), suggesting Toxoplasma's significant role in posterior uveitis.
  • About 14.4% of seropositive uveitis cases were linked to primarily acquired Toxoplasma infection, indicated by higher antibody levels in IFAT tests compared to IHAT tests.

Article Abstract

Anti Toxoplasma antibodies were sought in 34 patients with uveitis and 20 healthy individuals by IHAT and IFAT. The total sero-positivity rate was 26.5%. The prevalence was significantly higher among patients with posterior (42.9%) than with anterior uveitis (7.1%) and control (10%) indicating significant role of Toxoplasma as an aetiologic agent of posterior uveitis. 14.4% of patients with seropositive uveitis were considered to be due to primarily acquired Toxoplasma infection as evidenced by their significant higher IFAT mean titre (576.7 +/- 322.1) than IHAT (48 +/- 18.5). The reported toxoplasmic anterior uveitis case is most probably secondary to posterior involvement.

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