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Research on truck-drone collaborative route planning for rural logistics delivery services.
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December 2024
Department of Production Engineering, KTH Royal Institute of Technology, 11428, Stockholm, Sweden.
This study investigates the implementation of collaborative route planning between trucks and drones within rural logistics to improve distribution efficiency and service quality. The paper commences with an analysis of the unique characteristics and challenges inherent in rural logistics, emphasizing the limitations of traditional methods while highlighting the advantages of integrating truck and drone technologies. It proceeds to review the current state of development for these two technologies and presents case studies that illustrate their application in rural logistics.
View Article and Find Full Text PDFMaternal mortality in Italy estimated by the Italian Obstetric Surveillance System.
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December 2024
National Centre for Diseases Prevention and Health Promotion, Istituto Superiore di Sanità, Rome, Italy.
This study aimed to calculate Italy's first national maternal mortality ratio (MMR) through an innovative record-linkage approach within the enhanced Italian Obstetric Surveillance System (ItOSS). A record-linkage retrospective cohort study was conducted nationwide, encompassing all women aged 11-59 years with one or more hospitalizations related to pregnancy or pregnancy outcomes from 2011 to 2019. Maternal deaths were identified by integrating data from the Death Registry and national and regional Hospital Discharge Databases supported by the integration of findings from confidential enquiries conducted through active surveillance.
View Article and Find Full Text PDFImpacts of lateral conductive heat flow on ground temperature and implications for permafrost modeling.
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December 2024
Canada Centre for Remote Sensing, Canada Centre for Mapping and Earth Observation, Natural Resources Canada, 580 Booth Street, Ottawa, ON, K1A 0E4, Canada.
Permafrost ground temperature and its spatial distribution are usually calculated using one-dimensional models based on heat flow in the vertical direction. Here, we theoretically calculated the impacts of lateral conductive heat flow on ground temperature under equilibrium and transient conditions. The results show that lateral heat flow has strong impacts on ground temperature, especially in deep ground.
View Article and Find Full Text PDFThe relationship between mitochondrial health, telomerase activity and longitudinal telomere attrition, considering the role of chronic stress.
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December 2024
Department of Psychiatry and Behavioral Sciences and Weill Center for Neurosciences, University of California, San Francisco, CA, 94107, USA.
Telomere attrition is a hallmark of biological aging, contributing to cellular replicative senescence. However, few studies have examined the determinants of telomere attrition in vivo in humans. Mitochondrial Health Index (MHI), a composite marker integrating mitochondrial energy-transformation capacity and content, may be one important mediator of telomere attrition, as it could impact telomerase activity, a direct regulator of telomere maintenance.
View Article and Find Full Text PDFApplication of rapid genotyping of Warfarin individualized pharmacogenetic variants in Warfarin therapy.
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December 2024
Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, China.
Warfarin is the most widely used oral anticoagulant in clinical practice. The cytochrome P450 2C9 (CYP2C9), vitamin K epoxide reductase complex 1 (VKORC1), and cytochrome P450 4F2 (CYP4F2) genotypes are associated with warfarin dose requirements in China. Accurate genotyping is vital for obtaining reliable genotype-guided warfarin dosing information.
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