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PostCOVID-19 Impact on Perinatal Outcomes.
Diagnostics (Basel)
December 2024
City Rheumatology Center, Masanchi Street, 92, 050022 Almaty, Kazakhstan.
Severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) infection during pregnancy was associated with a number of adverse pregnancy outcomes, including miscarriage, preeclampsia, preterm birth, and stillbirth. The virus persistence can last for a long time, and the consequences of a previous coronavirus infection are currently under study. This study aimed to establish the clinical features of the course of pregnancy and childbirth in women with a history of asymptomatic coronavirus disease 2019 (COVID-19).
View Article and Find Full Text PDFRole of Arg1 ILC2s and ILCregs in gestational diabetes progression.
Sci Rep
January 2025
Department of Obstetrics and Gynecology, Reproductive Medicine Center, The First Affiliated Hospital of Anhui Medical University, Wanshui Road No. 120, Hefei, 230000, Anhui, China.
Innate lymphoid cells (ILCs) are a newly discovered subset of immune cells that are responsible for regulation of the immune microenvironment. In particular, the ILC categories ILC2s and regulatory ILCs (ILCregs) are associated with immunosuppression and chronic inflammation. Chronic low-grade inflammation leads to insulin resistance, a major etiological factor in gestational diabetes mellitus (GDM).
View Article and Find Full Text PDFDoes remote COVID infection in pregnancy affect the placenta and pregnancy outcomes? - Results from a prospective cohort study (PLACENTA IN COVID/ PIC study).
J Family Med Prim Care
December 2024
Department of Obstetrics and Gynaecology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.
Objectives: To study the rates of abnormal placentae and associated adverse perinatal outcomes in pregnant women who had COVID 19 infection during pregnancy, remote from delivery. To study the histopathological findings associated with these abnormal placentae.
Methods: A prospective cohort study was carried out, recruiting pregnant women with singleton gestation, who had COVID 19 infection during their pregnancy, remote from delivery between August 2021 to July 2022.
Ferumoxytol-enhanced MRI of retroplacental clear space disruption in placenta accreta spectrum.
Placenta
January 2025
Department of Radiology, Baylor College of Medicine, Houston, TX, 77030, USA; The Singleton Department of Radiology, Texas Children's Hospital, Houston, TX, 77030, USA. Electronic address:
Introduction: Placenta accreta spectrum (PAS) occurs when the placenta is pathologically adherent to the myometrium. An intact retroplacental clear space (RPCS) is a marker of normal placentation. In this study, we investigate use of the FDA-approved iron supplement ferumoxytol for contrast-enhanced MRI of the RPCS in mouse models of normal pregnancy and PAS.
View Article and Find Full Text PDFWe Should Perform a Systematic Evaluation of the Placenta.
J Ultrasound Med
January 2025
Department of Obstetrics and Gynecology and Reproductive Sciences, McGovern Medical School, University of Texas, Health Science Center at Houston (UTHealth), Houston, Texas, USA.
Despite its critical importance, the placenta receives substantially less attention during obstetric ultrasound examinations compared to the fetus. The evaluation of the placenta is typically limited to determining its location within the uterus, particularly its relationship to the cervix. Abnormal placenta findings are the result of gross anomalies identified by chance during obstetric examinations, rather than from a systematic evaluation.
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