Medicosocial problems engendered with the discovery of the Bell-Magendie Law.

Neurosurgery

Department of Neurosurgery, Wayne State University School of Medicine, Detroit Medical Center, Detroit, Michigan 48201, USA.

Published: July 2008

The discovery of the Bell-Magendie Law, which states that the ventral spinal roots transmit motor impulses and the posterior roots sensory impulses, established a major landmark in the history of neuroscience. It led to further elucidation of brain function and served as a starting point for virtually all of electrophysiology. During the past two centuries, there has been an intense debate as to which of the two scientists deserves the credit for the discovery itself and the prominent claim to the discovery. Extensive literature exists in this regard, and the goal of the authors is not to dwell on it further but rather to summarize the arguments. The major objective of this work, however, is to elaborate on the two medicosocial issues that were brought into focus by the discovery of the Bell-Magendie Law, namely, the provision of adequate numbers of cadavers for the sound anatomic education of medical students, so that the despicable practice of "body-snatching" could be abolished, and the prevention of cruelty to the experimental animals used for biomedical research. Public opinion prevailing at the time of the postulation of the Bell-Magendie Law promoted the establishment of the Royal Society for the Prevention of Cruelty to Animals, and other similar societies were established worldwide. The authors summarize the current status of these two issues.

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http://dx.doi.org/10.1227/01.NEU.0000335083.93093.06DOI Listing

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Medicosocial problems engendered with the discovery of the Bell-Magendie Law.

Neurosurgery

July 2008

Department of Neurosurgery, Wayne State University School of Medicine, Detroit Medical Center, Detroit, Michigan 48201, USA.

The discovery of the Bell-Magendie Law, which states that the ventral spinal roots transmit motor impulses and the posterior roots sensory impulses, established a major landmark in the history of neuroscience. It led to further elucidation of brain function and served as a starting point for virtually all of electrophysiology. During the past two centuries, there has been an intense debate as to which of the two scientists deserves the credit for the discovery itself and the prominent claim to the discovery.

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Since the early 19th century, significant controversy has persisted over the competing claims of two men, Charles Bell and François Magendie, to a pivotal discovery: that the dorsal spinal roots subserve sensation, whereas the ventral spinal roots subserve motion. However, the foundations of neuroanatomy on which Bell and Magendie built their research was formed two millennia in advance. Exploration of the work of four ancient scholars--Herophilus, Erasistratus, Aretaeus, and Galen--reveals a remarkable early appreciation of the separate neural pathways (if not the correct physiology) responsible for sensory and motor control.

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The French physiologist François Magendie showed, in 1822, that the anterior roots of the spinal nerves are motor and the posterior sensory. The English anatomist Charles Bell claimed the discovery, but his claim was based on republications of papers in which the wording had been altered to be consistent with Magendie's findings. Bell also appropriated Herbert Mayo's discoveries of the functions of the fifth and seventh cranial nerves.

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