Objective: This study describes a case of nodular fasciitis involving the hand and reviews the neoplasm's pertinent clinical, histologic, and pathologic features.

Methods: The patient's chart, operative record, histologic specimens, and relevant literature were reviewed.

Results: We report a case of nodular fasciitis involving the hand of a 55-year-old woman that was treated with marginal excision.

Conclusions: Nodular fasciitis is a self-limited, benign soft tissue tumor composed of fibroblasts and myofibroblasts that typically afflicts younger patients and rarely presents in the hand. Because of its presentation, it can be easily mistaken for a malignant neoplasm. However, most cases represent a reactive and therefore a polyclonal process. Marginal excision generally provides definitive treatment.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491338PMC

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