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Reading words versus seeing font or handwriting style: a study of hemifield processing.
Exp Brain Res
January 2025
Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, Canada.
Tachistoscopic studies have established a right field advantage for the perception of visually presented words, which has been interpreted as reflecting a left hemispheric specialization. However, it is not clear whether this is driven by the linguistic task of word processing, or also occurs when processing properties such as the style and regularity of text. We had 23 subjects perform a tachistoscopic study while they viewed five-letter words in either computer font or handwriting.
View Article and Find Full Text PDFComposite microRNA-genetic risk score model links to migraine and implicates its pathogenesis.
Brain
January 2025
Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.
The neurobiological mechanisms driving the ictal-interictal fluctuations and the chronification of migraine remain elusive. We aimed to construct a composite genetic-microRNA model that could reflect the dynamic perturbations of the disease course and inform the pathogenesis of migraine. We prospectively recruited four groups of participants, including interictal episodic migraine (i.
View Article and Find Full Text PDFRole of Psychological Factors in Migraine.
Cureus
December 2024
Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, CHN.
Migraine, marked by moderate to severe headaches, is frequently accompanied by reversible neurological symptoms. Recent studies have revealed a complex and significant relationship between psychological factors and the onset and progression of migraine. Personality traits, such as neuroticism and harm avoidance, play a crucial role in the development, progression, and treatment outcomes of migraines.
View Article and Find Full Text PDFClinical Relevance of 'Cap' and 'Track' Development after Recent Small Subcortical Infarct.
Ann Neurol
January 2025
Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK.
Objective: After a recent small subcortical infarct (RSSI), some patients develop perilesional or remote hyperintensities ('caps/tracks') to the index infarct on T2/FLAIR MRI. However, their clinical relevance remains unclear. We investigated the clinicoradiological correlates of 'caps/tracks', and their impact on long-term outcomes following RSSI.
View Article and Find Full Text PDFBrain tissue integrity in neuromyelitis optica spectrum disorder through T1-w/T2-w ratio, MTR and DTI.
J Neurol
January 2025
Department of Radiology and Oncology, Instituto de Radiologia. Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Rua Dr. Ovídio Pires de Campos, 75, Cerqueira César, São Paulo, 05403010, Brazil.
Background: The presence of diffuse brain damage in normal-appearing white matter (NAWM) and gray matter (NAGM) in neuromyelitis optica spectrum disorder (NMOSD) remains controversial. We aimed to address this controversy by applying a multiparametric MRI approach. Additionally, the association between MRI metrics and clinical variables was explored.
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