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Plasmid-mediated quinolone resistance determinants qnrA, qnrB, and qnrS among clinical isolates of Enterobacteriaceae in a Korean hospital. | LitMetric
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Plasmid-mediated quinolone resistance determinants qnrA, qnrB, and qnrS among clinical isolates of Enterobacteriaceae in a Korean hospital.

Migma Dorji Tamang Sung Yong Seol Jae-Young Oh Hee Young Kang Je Chul Lee Yoo Chul Lee Dong Taek Cho Jungmin Kim

Antimicrob Agents Chemother

Department of Microbiology, Kyungpook National University School of Medicine, Jung-gu, Daegu, Republic of Korea.

Published: November 2008

Screening of 368 consecutive nonreplicate clinical isolates of Enterobacteriaceae resistant to nalidixic acid and at least one extended-spectrum beta-lactam revealed the presence of qnrA, qnrB, and qnrS determinants, and identified novel qnrB variants, in Citrobacter freundii isolates. This study also revealed, for the first time, the linkage of qnrB, armA, and extended-spectrum and/or AmpC-type beta-lactamase genes on large conjugative plasmids.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573118PMC
http://dx.doi.org/10.1128/AAC.01633-07DOI Listing

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