Positive serology for dengue viral infection in pediatric patients with Kawasaki disease in southern Thailand.

Circ J

Division of Pediatric Cardiology, Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Songkhla, Kingdom of Thailand.

Published: September 2008

Background: The etiologic agent of Kawasaki disease (KD) is unknown, but may be dengue infection because of reported cases of concomitant KD and dengue.

Methods And Results: Prospective study was conducted to ascertain the relationship of positive serology for dengue infection in pediatric patients presenting with KD. A total of 65 cases were diagnosed with KD during the period of 4 years and of the 48 who had a complete dengue serologic study, 9 had a positive dengue titer.

Conclusion: In the present study 18.7% of patients had proven dengue infection from a positive serologic study. Further case-control study with other pediatric patients presenting with acute febrile illness needs to be done to support this significant finding.

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http://dx.doi.org/10.1253/circj.cj-08-0158DOI Listing

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