Primary non-Hodgkin's lymphomas of the gastrointestinal tract are rare in children, and few of these lymphomas are located in the sigmoid colon. The preoperative diagnosis rate is low. Complete resection is indicated if it can be done safely. Combination chemotherapy after resection is indicated.
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http://dx.doi.org/10.1016/j.amjsurg.2007.12.063 | DOI Listing |
Cureus
November 2024
Hematology and Oncology, State University of New York (SUNY) Downstate Health Sciences University, Brooklyn, USA.
Extranodal marginal zone lymphoma (EMZL) is a rare subtype of non-Hodgkin's lymphoma characterized by the malignant transformation of lymphoid tissue at sites affected by chronic inflammation. Pleural marginal zone lymphoma (PMZL) is an infrequent manifestation of this condition. We report a case of PMZL co-occurring with primary lung adenocarcinoma.
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November 2024
Oral Surgery, Faculty of Dentistry, Paris City University, Paris, FRA.
Lymphomas are malignant proliferations of B or T lymphocytes, classified as Hodgkin or non-Hodgkin lymphomas. The malignant proliferation of lymphoid cells mainly occurs in lymph nodes, but in a small number of cases, it can be extranodal. The oral cavity represents a very rare primary extra-nodal location for non-Hodgkin lymphoma and can pose a diagnostic challenge for the dentist.
View Article and Find Full Text PDFRadiol Case Rep
February 2025
Department of Radiology, Yantaishan Hospital, Yantai City, Shandong Province, China.
Primary non-Hodgkin's lymphoma (NHL) occurring in the cauda equina region within the spinal canal is exceedingly rare. It is characterized by severe clinical symptoms, a high rate of misdiagnosis, rapid progression, poor prognosis, and significant metastasis potential. In this paper, we report 1 case of a 58-year-old female with primary NHL and another case of a 69-year-old male with secondary NHL.
View Article and Find Full Text PDFFront Pharmacol
November 2024
Drug Clinical Trial Center, Shanghai Xuhui Central Hospital/Xuhui Hospital, Fudan University, Shanghai, China.
Introduction: Amdizalisib (HMPL-689) is an ATP-competitive PI3Kδ inhibitor currently under investigation for treating Hodgkin's lymphoma. This study aimed to evaluate the metabolism, excretion, pharmacokinetics, and safety profile of amdizalisib in healthy human subjects to support its clinical application.
Methods: This Phase I clinical trial included six healthy Chinese male volunteers who received a single oral dose of 30 mg/100 µCi [C]amdizalisib suspension.
Primary vulvar diffuse large B-cell lymphoma is a diagnostically challenging malignant tumor due to its low incidence and diverse clinical presentations. It has a good prognosis and is usually radio-chemotherapy-responsive. This case report emphasizes considering lymphoma as a differential in vulvar inflammatory conditions.
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