AI Article Synopsis
- The study aimed to assess the levels of eosinophil major basic protein (MBP) in patients with chronic rhinosinusitis (CRS) and its potential role in the condition's development.
- Thirty-eight nasal mucus samples from CRS patients were analyzed using an Elisa assay, compared to thirty samples from healthy individuals as a control group.
- Results showed that MBP levels were significantly higher in CRS patients’ mucus, indicating that MBP may play a key role in the pathogenesis of CRS.
Article Abstract
Objective: To evaluate the expression of eosinophil major basic protein (MBP) in chronic rhinosinusitis (CRS) and discuss the role of MBP in the pathogenesis in CRS.
Method: Thirty-eight nasal mucus obtained from CRS patients were used to detect the expression of MBP by Elisa assay. Thirty nasal mucus samples from health people were used as control.
Result: The expression of MBP of nasal mucus obtained from CRS patients was obviously higher than that of nasal mucus obtained from control. There was significant statistical difference (P < 0.01).
Conclusion: MBP was involved in the formation of CRS.
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