Serum 18:2 (9, 11) linoleic acid concentration was measured in normal pregnancy and pre-eclampsia. The 18:2 (9, 11) linoleic acid in normal pregnancy increased progressively with advancing gestation, reaching the highest value at the end of pregnancy. The 18:2 (9, 11) linoleic acid concentration in pregnancy complicated by pre-eclampsia was significantly higher than in normal pregnancy after week 28. It is suggested that measurement of the 18:2 (9, 11) linoleic acid concentration in plasma may be useful as a predictor of the likely development of pre-eclampsia.
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