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Morphological Analysis of the Retrotalar Pulley and Its Role in Flexor Hallucis Longus Impingement: Insights from a CT-Based Study.
J Foot Ankle Surg
January 2025
Institute for Locomotion, Center for Arthritis Surgery, Sainte-Marguerite Hospital, Aix-Marseille University, 270 Boulevard de Sainte-Marguerite, 13009, Marseille, France.
The Flexor Hallucis Longus (FHL) is a muscle that can be subject to multiple conflicts. The most common conflict is due to inflammation of the tendon at the retrotalar pulley. The constraints exerted on the FHL are responsible for a pathology called functional Hallux Limitus.
View Article and Find Full Text PDFBacterial sensor evolved by decreasing complexity.
Proc Natl Acad Sci U S A
February 2025
Department of Biotechnology and Environmental Protection, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, Granada 18008, Spain.
Bacterial receptors feed into multiple signal transduction pathways that regulate a variety of cellular processes including gene expression, second messenger levels, and motility. Receptors are typically activated by signal binding to ligand-binding domains (LBDs). Cache domains are omnipresent LBDs found in bacteria, archaea, and eukaryotes, including humans.
View Article and Find Full Text PDFAn Innovative Use of Maxillofacial Implants for the Open Reduction and Internal Fixation of a Displaced Sternal Fracture: A Case Report.
Cureus
December 2024
Oral and Maxillofacial Surgery, Nagoya Tokushukai General Hospital, Kasugai, JPN.
Sternal fractures resulting from blunt chest trauma often present unique surgical challenges. While conservative management is common, cases with significant displacement, delayed union, or painful dyspnea may require surgical intervention to improve structural stability and relieve symptoms. Here, we report the case of a 46-year-old man who sustained a displaced sternal fracture in a motor vehicle accident.
View Article and Find Full Text PDFOn the substrate turnover rate of NBCe1 and AE1 SLC4 transporters: structure-function considerations.
Front Physiol
January 2025
Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.
A transport protein's turnover rate (TOR) is the maximum rate of substrate translocation under saturating conditions. This parameter represents the number of transporting events per transporter molecule (assuming a single transport site) per second (s). From this standpoint, a transporter's TOR is similar to an enzyme's catalytic constant.
View Article and Find Full Text PDFAnatomic variations in origin and coursing of the transverse cervical artery: morphogenesis and relation to the high arch-shaped subclavian artery.
Anat Sci Int
January 2025
Department of Anatomy, The Nippon Dental University School of Life Dentistry at Niigata, Niigata, Japan.
This case report presents an atypical transverse cervical artery with its detailed anatomy, morphogenesis, and association with the high arch-shaped subclavian artery. The atypical arteries, related arteries, and adjacent cervical and brachial plexuses were macroscopically examined in a 98-year-old Japanese female cadaver donated to The Nippon Dental University for medical education and research. The atypical deep branch of the transverse cervical artery originated from the internal thoracic artery and passed through between the C5 and C6 roots, in close contact with the C5 and C6 junction, to reach the dorsal side of the brachial plexus.
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