Unusual production of glutathione in Actinobacteria.

Arch Microbiol

Department of Biology, California State University-Fresno, Fresno, CA 93740, USA.

Published: January 2009

Most Actinobacteria produce mycothiol as the major thiol. In addition to mycothiol Rhodococcus AD45 generates a substantial level of glutathione possibly using genes acquired in a lateral transfer. Instead of mycothiol, Rubrobacter radiotolerans and Rubrobacter xylanophilus produce glutathione, whose synthesis appears to involve enzymes substantially different from those in other organisms.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605195PMC
http://dx.doi.org/10.1007/s00203-008-0423-1DOI Listing

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