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Recent advances in HPV biotechnology: Understanding host-virus interactions and cancer progression-a review.
Int J Surg
October 2024
Department of Pharmacy, College of Medicine and Health Sciences, Ambo University, Ambo, Ethiopia.
Cervical cancer ranks as the fourth most common cancer among women globally, posing a significant mortality risk. Persistent infection with high-risk human papillomavirus (HPV) is the primary instigator of cervical cancer development, often alongside co-infection with other viruses, precipitating various malignancies. This study aimed to explore recent biotechnological advances in understanding HPV infection dynamics, host interactions, and its role in oncogenesis.
View Article and Find Full Text PDFStructural Optimization of Natural Plant Products: Construction, Pesticidal Activities, and Toxicology Study of New 2-Isopropanol-4-methoxy-7-alkyl/aryloxycarbonyl-()-vinyl-2,3-dihydrobenzofurans.
J Agric Food Chem
January 2025
College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, China.
Recently, the structural optimization of natural bioactive products has been one of the important ways to discover new pesticide candidates. Based on osthole as a lead compound, herein, a series of new 2-isopropanol-4-methoxy-7-alkyl/aryloxycarbonyl-()-vinyl-2,3-dihydrobenzofuran derivatives were synthesized. Steric configurations of compounds , , , , , , and were confirmed by X-ray monocrystallography.
View Article and Find Full Text PDFTropical forest clearance impacts biodiversity and function, whereas logging changes structure.
Science
January 2025
Department of Biology & Leverhulme Centre for Nature Recovery, University of Oxford, Oxford, UK.
The impacts of degradation and deforestation on tropical forests are poorly understood, particularly at landscape scales. We present an extensive ecosystem analysis of the impacts of logging and conversion of tropical forest to oil palm from a large-scale study in Borneo, synthesizing responses from 82 variables categorized into four ecological levels spanning a broad suite of ecosystem properties: (i) structure and environment, (ii) species traits, (iii) biodiversity, and (iv) ecosystem functions. Responses were highly heterogeneous and often complex and nonlinear.
View Article and Find Full Text PDFImpacts of EPA's finalized power plant greenhouse gas standards.
Science
January 2025
Center for Global Sustainability, University of Maryland, College Park, MD, USA.
Emissions reductions may be met with relatively small costs.
View Article and Find Full Text PDFGrazing can reduce wildfire risk amid climate change.
Science
January 2025
Valério D. Pillar is at the Laboratório de Ecologia Quantitativa, Departamento de Ecologia/Centro de Ecologia, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Over half of Earth's land surface is covered with fire-prone vegetation, with grassy ecosystems-such as grasslands, savannas, woodlands, and shrublands-being the most extensive. In the context of the climate crisis, scientists worldwide are exploring adaptation measures to address the heightened fire risk driven by more frequent extreme climatic conditions such as droughts and heatwaves, as well as by non-native plant invasions that increased fuel loads and altered fire regimes. Although fire is intrinsic to grassy ecosystems, rising exposure to wildfire smoke harms human health and the environment.
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