The early ANTP gene repertoire: insights from the placozoan genome.

PLoS One

Division of Ecology and Evolution, Stiftung Tieraerztliche Hochschule Hannover, Hannover, Germany.

Published: August 2008

AI Article Synopsis

  • Scientists are studying ANTP genes in animals to understand how they have changed over time, but there are different ideas about how this happened.* -
  • Recently, scientists looked closely at the complete genome of a simple organism called Trichoplax adhaerens, which may show important information about early animal ancestors.* -
  • They found some special genes in Trichoplax that are similar to genes in other animals, suggesting that a long time ago, all these animals might have shared a common ancestor with basic gene structures.*

Article Abstract

The evolution of ANTP genes in the Metazoa has been the subject of conflicting hypotheses derived from full or partial gene sequences and genomic organization in higher animals. Whole genome sequences have recently filled in some crucial gaps for the basal metazoan phyla Cnidaria and Porifera. Here we analyze the complete genome of Trichoplax adhaerens, representing the basal metazoan phylum Placozoa, for its set of ANTP class genes. The Trichoplax genome encodes representatives of Hox/ParaHox-like, NKL, and extended Hox genes. This repertoire possibly mirrors the condition of a hypothetical cnidarian-bilaterian ancestor. The evolution of the cnidarian and bilaterian ANTP gene repertoires can be deduced by a limited number of cis-duplications of NKL and "extended Hox" genes and the presence of a single ancestral "ProtoHox" gene.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515636PMC
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0002457PLOS

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