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Preliminary report: Protective effects of probiotics on cefovecin-induced gut dysbiosis in dogs.
Can J Vet Res
January 2025
Laboratory of Veterinary Dermatology (Han, Hwang) and Research Institute for Veterinary Science (Han, Mun, Hwang), College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea; ORIGIN Veterinary Dermatology Clinic, Busan, Republic of Korea (Kang); Department of Companion Animal Health Care, College of Medical Health, Kyungbok University, Namyangju, Republic of Korea (Kim S-J); Department of Large Animal Internal Medicine, College of Veterinary Medicine, Kangwon National University, Chuncheon, Republic of Korea (Kim Y-H).
The objective of this study was to evaluate whether supplementation with probiotics over a 2-week period stabilizes the gut microbiota in dogs following prolonged cefovecin treatment. A significant number of clinical veterinarians prescribe oral probiotics to dogs in conjunction with systemic antibiotics with the intention of protecting against gut dysbiosis. The effects of antibiotics and probiotics in dogs have not been extensively studied, however, and the optimal treatment for gut dysbiosis remains uncertain.
View Article and Find Full Text PDFE. coli Nissle 1917 improves gut microbiota composition and serum metabolites to counteract atherosclerosis via the homocitrulline/Caspase 1/NLRP3/GSDMD axis.
Int J Med Microbiol
December 2024
Insititute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, International Joint Laboratory for Arteriosclerotic Disease Research of Hunan Province, University of South China, Hengyang, Hunan 421001, China. Electronic address:
Background: The probiotic E. coli Nissle 1917 (EcN) alleviates the progression of various diseases, including colitis and tumors. However, EcN has not been studied in atherosclerosis.
View Article and Find Full Text PDFGut Commensal Barnesiella Intestinihominis Ameliorates Hyperglycemia and Liver Metabolic Disorders.
Adv Sci (Weinh)
December 2024
State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 211198, China.
Recent studies have highlighted the role of the gut microbiota in type 2 diabetes (T2D). Improving gut microbiota dysbiosis can be a potential strategy for the prevention and management of T2D. Here, this work finds that the abundance of Barnesiella intestinihominis is significantly decreased in the fecal of T2D patients from 2-independent centers.
View Article and Find Full Text PDFThe Combination of Tumor-targeting A1-R Plus the Autophagy-inhibitor Chloroquine Synergistically Eradicates HT1080 Fibrosarcoma Cells and .
In Vivo
December 2024
AntiCancer Inc., San Diego, CA, U.S.A.;
Background/aim: Salmonella typhimurium A1-R (A1-R) targets and inhibits a wide range of cancer types without continuously infecting healthy tissue. Chloroquine, an antimalarial drug, induces apoptosis and inhibits autophagy in cancer cells. The aim of the present study was to determine the synergy of A1-R plus chloroquine on HT1080 human fibrosarcoma cells in vitro and in a nude-mouse model.
View Article and Find Full Text PDFMetabolic acidosis due to d-lactate in a patient with intestinal resection: Diagnostic challenges and nutritional strategies.
Int J Surg Case Rep
December 2024
Faculty of Health, Universidad Santiago de Cali, Cali, Colombia. Electronic address:
Introduction: Metabolic acidosis, marked by decreased plasma bicarbonate and arterial pH, is a common complication following extensive abdominal surgeries. D-lactate acidosis presents additional diagnostic challenges due to nonspecific symptoms.
Presentation Of Case: A 65-year-old woman with hypertension and morbid obesity was admitted to the ICU for intestinal obstruction and peritonitis due to an incarcerated hernia.
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