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Interrelationship between chemsex engagement and PrEP (pre-exposure prophylaxis) experience in men who have sex with men: a community-based cross-sectional study.
Sex Transm Infect
January 2025
Stanley Ho Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Hong Kong, Hong Kong, China
Background: Chemsex engagement is known to be associated with higher-risk sexual behaviour, HIV and sexually transmitted infection (STI). To reduce HIV infection risk, pre-exposure prophylaxis (PrEP) is increasingly used in the men who have sex with men (MSM) community. This study aims to examine the interrelationship between chemsex engagement and PrEP use in MSM.
View Article and Find Full Text PDFVulvar Developmental Stages During Puberty: A Systematic Review.
J Pediatr Adolesc Gynecol
January 2025
Department of Women, Children, and Adolescents, Geneva University Hospitals, Geneva, Switzerland.
Study Objective: Puberty is associated with important changes in secondary sexual characteristics, but the changes occurring in female external genitalia are not thoroughly described. The aim of this systematic review is to summarize and assess the current scientific knowledge regarding vulvar changes and development during puberty.
Methods: PubMed, Embase, Web of Science, and Cochrane were searched, using keywords related to "puberty", "vulva", and "morphology".
Single-cell RNA-seq identifies protracted mouse germline X chromosome reactivation dynamics directed by a PRC2-dependent mechanism.
Dev Cell
January 2025
King's College London, Centre for Gene Therapy and Regenerative Medicine, School of Basic & Medical Biosciences, Faculty of Life Sciences and Medicine, London, UK; King's College London, Guy's Hospital Assisted Conception Unit, Department of Women and Children's Health, School of Life Course and Population Sciences, Faculty of Life Sciences and Medicine, London, UK. Electronic address:
Female primordial germ cells (PGCs) undergo X chromosome reactivation (XCR) during genome-wide reprogramming. XCR kinetics and dynamics are poorly understood at a molecular level. Here, we apply single-cell RNA sequencing and chromatin profiling on germ cells from F mouse embryos, performing a precise appraisal of XCR spanning from migratory-stage PGCs to gonadal germ cells.
View Article and Find Full Text PDFInfluence of carcass chilling time on the progression of rigor mortis, carcass characteristics and physicochemical properties related to the colour and tenderness of longissimus thoracis et lumborum and biceps femoris muscles in Botucatu rabbits.
Meat Sci
January 2025
Department of Agricultural and Environmental Biotechnology, Faculty of Agriculture and Veterinary Sciences, São Paulo State University, 14884-900 Jaboticabal, Brazil.
The objective of this study was to characterize the progression of rigor mortis and evaluate the influence of chilling time on carcass characteristics, colour, and tenderness of Botucatu rabbit meat in both males and females. The muscles analyzed were the longissimus thoracis et lumborum (LTL) and biceps femoris (BF). As chilling time progressed, weight loss due to chilling increased (P < 0.
View Article and Find Full Text PDFExploring canine mast cell tumors: An investigation into demographic characteristics, and grading system analysis from a pathology lab data (2019-2021).
Prev Vet Med
January 2025
DNAtech, Laboratório Veterinário, Lisboa, Portugal; CECAV, Centro de Ciência Animal e Veterinária, Faculdade de Medicina Veterinária, Universidade Lusófona-Centro Universitário de Lisboa, Portugal; CBIOS - Centro de Investigação em Biociências e Tecnologias da Saúde - Universidade Lusófona, Lisboa, Portugal.
Mast cell tumors (MCT) are among the most common neoplasia in dogs, representing up to 21 % of skin tumors. However, etiology and risk factors for its development remain unclear. This study aimed to reduce this knowledge gap by comprehensively analyzing 905 MCT cases diagnosed in Portugal between 2019 and 2021, using descriptive and inferential analyses.
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