Comparison of protocols efficacy in poor responders: differences in oocytes/embryos competence with different protocols, a retrospective study.

Fertil Steril

Maternal-Pediatric Department, Pordenone Hospital, Pathophysiology Unit of Human Reproduction and Sperm Bank, Pordenone, Italy.

Published: April 2009

At present, there is no agreement on poor ovarian response definition, and no definitive evidence that this prognosis can be changed by a specific protocol. Our data suggest that a flare-up protocol with a depot gonadotropin-releasing hormone (GnRH) agonist formulation gives higher total pregnancy and implantation rates than a GnRH antagonist, possibly by improving oocyte/embryo competence.

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http://dx.doi.org/10.1016/j.fertnstert.2008.06.001DOI Listing

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