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Comparative Assessment of Real-Time and Offline Short-Lag Spatial Coherence Imaging of Ultrasound Breast Masses.
Ultrasound Med Biol
March 2025
Department of Computer Science, Johns Hopkins University, Baltimore, MD, USA; Department of Electrical & Computer Engineering, Johns Hopkins University, Baltimore, MD, USA; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA. Electronic address:
Objective: To perform the first known investigation of differences between real-time and offline B-mode and short-lag spatial coherence (SLSC) images when evaluating fluid or solid content in 60 hypoechoic breast masses.
Methods: Real-time and retrospective (i.e.
In vitro study of a siRNA delivery liposome constructed with an ionizable cationic lipid.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
October 2024
Department of Pharmaceutical Engineering, Chemistry and Chemical Engineering, Central South University, Changsha 410083.
Objectives: Small interfering RNA (siRNA) can silence disease-related genes through sequence-specific RNA interference (RNAi). Cationic lipid-based liposomes effectively deliver nucleic acids into the cytoplasm but often exhibit significant toxicity. This study aims to synthesize a novel ionizable lipid, Nε-laruoyl-lysine amide (LKA), from natural amino acids, constructed LKA-based liposomes, and perform physicochemical characterization and cell-based experiments to systematically evaluate the potential of these ionizable lipid-based liposomes for nucleic acid delivery.
View Article and Find Full Text PDFDiagnostic accuracy comparison of the Fluorion MTBC QLP 2.1 real-time PCR and the COBAS TaqMan MTB assays for Mycobacterium tuberculosis detection.
J Microbiol Methods
March 2025
Molecular Biology Laboratory, Institut Pasteur du Maroc, Casablanca, Morocco.
The Fluorion MTBC QLP 2.1 Real-Time PCR test is a valuable alternative for tuberculosis diagnosis, demonstrating 100 % specificity and 87.5 % sensitivity for respiratory specimens, 97.
View Article and Find Full Text PDFGlobal Incidence, Risk Factors, and Temporal Trends of Adrenal Cancer: a systematic analysis of cancer registries.
Endocr Pract
March 2025
The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong SAR, China; Centre for Health Education and Health Promotion, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China; Department of Global Health, School of Public Health, Peking University, Beijing, China. Electronic address:
Objectives: Adrenal gland cancer (AGC) is a rare cancer with a poor prognosis. Studies on this cancer have been limited. This study, for the first time, aims to analyse the global disease burden and trends of adrenal gland cancer in country level and examine lifestyle and socioeconomic risk factors to generate hypotheses.
View Article and Find Full Text PDFUnplanned Return to the Operating Room After Cataract Surgery.
Am J Ophthalmol
March 2025
Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Electronic address:
Objective: To determine the rate of unplanned return to operation room (OR) within 90 days of cataract surgery and to identify the most common pre-operative and intraoperative risk factors.
Design: Retrospective case-control study.
Subjects And Controls: Patients aged >= 40 years undergoing cataract surgery at the Wilmer Eye Institute between 2019-2022 with at least 90 days of postoperative follow-up were included.
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