The question of why some immunization programmes in sub-Saharan Africa are more successful than others is an intriguing one, but not one that is frequently raised or investigated. Borrowing techniques from both performance benchmarking and positive deviance inquiry, we explored this question in six countries. We first set out to define for a systematic sample of countries the key constructs commonly associated with improving immunization coverage, using an inductive, 'insider' point of view. We then explored their utility in generating hypotheses about coverage differences across countries through a preliminary application of the measures of these constructs to the countries in this sample. Our findings suggest that there are different paths to success, and that not only what countries do, but how they execute their programmes, seem to make a difference in coverage outcomes. In some cases, extramural, contextual factors may also help to explain these differences. We discuss several hypotheses generated by our study, identify methodological limitations, and recommend improvements to the methods we used. Similar formative studies are needed to validate our preliminary hypotheses, to generate new ones, and to raise our level of confidence in the early policy implications that we see emerging from our preliminary work in this area. Eventually, testing of the hypotheses generated by this and other formative studies could generate a robust theory of why some programmes are more successful than others, a phenomenon likely to be relevant to other child and maternal health programmes in sub-Saharan Africa.
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http://dx.doi.org/10.1093/heapol/czn028 | DOI Listing |
BMJ Oncol
May 2024
Department of Clinical Oncology, Cancer Diseases Hospital, Lusaka, Zambia.
Objectives: Locally led research on cancer is needed in sub-Saharan Africa to set feasible research priorities that inform national policy. The aim of this project was to develop a research agenda for national cancer control planning, using a nationally driven approach, focused on barriers to diagnosis and high-quality treatment for prostate cancer in Zambia.
Methods And Analysis: This was a Delphi process.
J Acquir Immune Defic Syndr
January 2025
Community Health and Social Sciences Department and Institute for Implementation Science in Population Health (ISPH), Graduate School of Public Health and Health Policy, City University of New York (CUNY), New York, NY, USA.
Background: Preventing HIV infections among adolescents and young adults (AYA) is crucial for curtailing the epidemic. Oral pre-exposure prophylaxis (PrEP) is a highly effective prevention method increasingly available to this age group in sub-Saharan Africa but population-based data on awareness and use of PrEP among AYA remains limited.
Methods: Analyzing survey data from two rounds of the Rakai Community Cohort Study, an open, population-based cohort, we estimated prevalence ratios associating various sociodemographic characteristics with PrEP awareness and ever-use among 15- to 24-year-olds in south-central Uganda between 2018 and 2023.
Malar J
January 2025
MRC Centre for Global Infectious Disease Analysis, Imperial College London, London, UK.
Background: The availability of many tools for malaria control leads to complex decisions regarding the most cost-effective intervention package based on local epidemiology. Mosquito characteristics influence the impact of vector control, but entomological surveillance is often limited due to a lack of resources in national malaria programmes.
Methods: This study quantified the monetary value of information provided by entomological data collection for programmatic decision-making using a mathematical model of Plasmodium falciparum transmission.
J Head Trauma Rehabil
January 2025
Author Affiliations: Boston University School of Public Health, Boston, Massachusetts (Ms Sherman Rosa); Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts (Mr Nadal); and Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts (Dr Saadi).
Objective: This study assessed (1) the feasibility and usability of traumatic brain injury (TBI) assessment using the Ohio State University TBI Identification Method (OSU-TBI-ID) in a sample of English and Spanish-speaking refugees and asylum seekers (hereafter refugees), and (2) the prevalence and characteristics of TBI in this population.
Setting And Participants: Refugees seeking care from Massachusetts General Hospital (MGH) Asylum Clinic, the MGH Chelsea HealthCare Center, and other asylum programs in the Greater Boston Area.
Design And Main Measures: Bilingual clinical research coordinators screened 158 English and Spanish-speaking refugees using the OSU-TBI-ID.
Heliyon
January 2025
Genetics, Biotechnology and Seed Science Unit (GBioS), Laboratory of Crop Production, Physiology and Plant Breeding, Faculty of Agronomic Sciences, University of Abomey-Calavi, 01 BP 526 Tri Postal Cotonou, Benin.
Regularly consuming orange-fleshed sweet potatoes (OFSP) is widely recognised as an effective way to treat vitamin A deficiency (VAD), particularly in low-income countries. Unfortunately, cultivars of OFSP are poorly disseminated in most countries in sub-Saharan Africa, where VAD is a major cause of blindness. This study was conducted to evaluate the effect of the genotype-environment interaction (GEI) on the performance and stability of the yield components of OFSP cultivars to trigger their adoption by farmers.
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