Cementless acetabular components are routinely used in revision hip surgery. Nevertheless, few investigators have assessed their retention and efficacy over the long term. This occurs mainly in cases which originate from moderate to severe bone losses (cavitary and or segmental) requiring the use of morselized and or bulk bone graft. Our objective in the present study is to report the outcome of 42 patients with 43 cementless acetabular revisions with bone graft who were operated by the same surgeon. The report is based on the clinical and radiographic evaluation of the patients alive at 167 months of follow-up.
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http://dx.doi.org/10.1016/j.arth.2007.11.022 | DOI Listing |
Eur Arch Otorhinolaryngol
March 2025
Otolaryngology Research Center, Department of Otolaryngology-Head and Neck Surgery, Tehran University of Medical Sciences, Imam Khomeini Medical Complex, Tehran, Iran.
Purpose: To evaluate the ototoxicity of povidone iodine (PVP-I) at concentrations of 5% and 10% during tympanoplasty by assessing frequency-specific audiometric outcomes and graft success rates in a large cohort of patients.
Methods: This prospective, triple-blinded, randomized clinical trial enrolled 542 patients undergoing primary tympanoplasty. After excluding patients for inadequate follow-up, 204 ears received 10% PVP-I and 199 ears received 5% PVP-I.
Bone Marrow Transplant
March 2025
Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) aims to cure patients without inducing severe graft-versus-host disease (GVHD) or relapse. In prospective studies of mostly pediatric patients with haploidentical donors, ex vivo αβTCR/CD19 depletion has shown to have low incidences of GVHD, but data for adults with matched related (MRD) or unrelated donors (MUD) remain limited. We analyzed the outcomes of recipients who received a myeloablative regimen plus ATG, followed by an αβTCR/CD19-depleted allograft (cohort D+ATG (n = 122)), and compared outcomes to T cell-replete cohorts (cohort R (N = 60)); without ATG; R+ATG = with ATG (N = 129) in a single-center retrospective analysis.
View Article and Find Full Text PDFClin Exp Dent Res
February 2025
Department of Dentistry, San Raffaele Hospital, Vita Salute University, Milan, Italy.
Objectives: This article aims to present a proof-of-concept surgical technique for immediate reconstruction of zygoma anatomy following implant failure and complications, illustrating the related clinical steps in a cadaver specimen. Zygomatic implants represent a paradigm shift, addressing challenges posed by severe maxillary bone atrophy and partial or complete maxillectomy, not suitable for conventional dental implant placement. Despite documented high survival rates, intra- and postoperative complications can occur and lead to implant failure, resulting in severe defects extended up to entire height of zygomatic bone pyramid.
View Article and Find Full Text PDFEur J Haematol
March 2025
Hematopoietic Stem Cell Transplantation and Cellular Therapy Program, Division of Hematology/Oncology, Department of Medicine, University of California Irvine, Irvine, California, USA.
Background: Data on bone marrow (BM) findings in secondary hemophagocytic lymphohistiocytosis (sHLH) and their association with overall survival (OS) are limited.
Objectives: This study aimed to develop a prognostic model incorporating BM findings and clinico-laboratory factors affecting OS.
Methods: We retrospectively evaluated 50 adults with sHLH and developed a clinicopathological prognostic model based on survival-associated factors.
BMC Surg
March 2025
Department of Orthopedic, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China.
Objective: To evaluate the clinical efficacy of repairing bone defects caused by benign bone tumors using allograft bone combined with calcium phosphate bone powder.
Methods: A retrospective analysis was conducted on 55 patients (aged 10-61 years, mean 35 ± 13.2) with benign bone tumors treated at our hospital from June 2020 to December 2022.
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