According to a recent Center for Disease Control survey, 33% of the US population is obese. Because labeled dosing guidelines are based upon non-obese individuals, under dosing of antibiotics may be problematic in this population. We developed an automated dose checking tool to efficiently detect potentially inappropriate dosing of antibiotics in bariatric (morbidly obese patients).
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Micron
January 2025
Department of Materials Science and Engineering, The Iby and Aladar Fleischman Faculty of Engineering, Tel Aviv University, Tel Aviv 6997801, Israel. Electronic address:
Atomic-scale metrology in scanning transmission electron microscopy (STEM) allows to measure distances between individual atomic columns in crystals and is therefore an important aspect of their structural characterization. Furthermore, it allows to locally resolve strain in crystals and to calibrate precisely the pixel size in STEM. We present a method dedicated to the evaluation of interplanar spacing (d-spacing) based on an algorithm including curve fitting of processed high-angle annular dark-field STEM (HAADF STEM) signals.
View Article and Find Full Text PDFCureus
January 2025
General Practice, Wad Medani Hospital, Wad Medani, SDN.
To enhance patient outcomes in pediatric cancer, a better understanding of the medical and biological risk variables is required. With the growing amount of data accessible to research in pediatric cancer, machine learning (ML) is a form of algorithmic inference from sophisticated statistical techniques. In addition to highlighting developments and prospects in the field, the objective of this systematic study was to methodically describe the state of ML in pediatric oncology.
View Article and Find Full Text PDFAAPS PharmSciTech
January 2025
Department of Mechanical and Nuclear Engineering, Virginia Commonwealth University, Richmond, VA, United States of America.
The administration of surfactant aerosol therapy to preterm infants receiving continuous positive airway pressure (CPAP) respiratory support is highly challenging due to small flow passages, relatively high ventilation flow rates, rapid breathing and small inhalation volumes. To overcome these challenges, the objective of this study was to implement a validated computational fluid dynamics (CFD) model and develop an overlay nasal prong interface design for use with CPAP respiratory support that enables high efficiency powder aerosol delivery to the lungs of preterm infants when needed (i.e.
View Article and Find Full Text PDFPhys Med
January 2025
IRCCS Humanitas Research Hospital, Radiotherapy and Radiosurgery Department, via Manzoni 56, 20089 Rozzano, Milan, Italy.
Purpose: Total marrow (lymph-node) irradiation (TMI/TMLI) is a radiotherapy technique irradiating the whole body of a patient. The limited couch travel range in modern linacs (130-150 cm) forces to split the TMI/TMLI delivery into two plans with opposite orientation. A dedicated field junction is necessary to achieve satisfactory target coverage in the overlapping region of the two plans.
View Article and Find Full Text PDFAppl Radiat Isot
January 2025
School of Physics and Electronic Engineering, Sichuan University of Science and Engineering, Yibin, 644005, China.
The three-dimensional radiation field is an important database reflecting the radioactivity distribution in a nuclear facility. It is of great significance to accurately and quickly grasp the radiation dose field distribution to implement radiation protection. Presently, majority of radiation field reconstruction algorithms concentrate on two-dimensional reconstruction and can only measure on a regular grid.
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