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Primary Leiomyosarcoma of the Thyroid.
Head Neck Pathol
January 2025
Department of medical oncology, Habib Bourguiba Hospital, University of Sfax, Sfax, 3029, Tunisia.
Leiomyosarcoma (LMS) is a malignant mesenchymal neoplasm showing smooth muscle differentiation. Primary LMS of the thyroid gland is quite rare, accounting for only 0.014% of cases.
View Article and Find Full Text PDFCellular Schwannoma Arising After the Resection of an Anterior Mediastinal Leiomyosarcoma.
Ann Thorac Surg Short Rep
December 2024
Department of General Thoracic Surgery, National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Kure, Japan.
Cellular schwannoma is a schwannoma subtype with histopathologic features resembling those of malignant tumors. We report a case of a cellular schwannoma arising at the resection margin of an anterior mediastinal leiomyosarcoma. An 88-year-old woman who had undergone resection of an anterior mediastinal leiomyosarcoma 2 years previously developed a mediastinal tumor at the resection margin, raising suspicion of leiomyosarcoma recurrence.
View Article and Find Full Text PDFLeiomyosarcoma of the colon. An uncommon condition.
Rev Esp Enferm Dig
January 2025
Cirugía General, Complejo Hospitalario Universitario de Cartagena.
The gastrointestinal leiomyosarcoma is a rare tumor of the colon that arises from the smooth muscle cells of the intestinal wall. It is a very aggressive tumor with a poor prognosis.
View Article and Find Full Text PDFGenomic characterization and histologic analysis of uterine leiomyosarcoma arising from leiomyoma with bizarre nuclei.
J Pathol
February 2025
Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Leiomyoma with bizarre nuclei (LM-BN) is a rare variant of leiomyoma with a benign clinical course. In contrast, leiomyosarcoma (LMS) is a high-grade, malignant neoplasm characterized by high recurrence rates and poor survival. While LM-BN and LMS show distinct morphologies, they share similar immunoprofiles and molecular alterations, with both considered 'genomically unstable'.
View Article and Find Full Text PDFInferior vena cava leiomyosarcoma mimicking an exophytic intrahepatic cholangiocarcinoma.
Intractable Rare Dis Res
November 2024
Department of Radiology & Diagnostic Imaging, University of Alberta Hospital, Edmonton, Canada.
Inferior vena cava (IVC) leiomyosarcomas are rare smooth muscle neoplasms that account for 0.5% of adult soft tissue sarcomas. They present with nonspecific symptoms and have poor prognosis.
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