Through the synthesis of a focused library and SAR investigations, a more potent analogue of gemmacin (discovered in a previous diversity-oriented synthesis (DOS) campaign), gemmacin B, was discovered.
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Gemmacin B: bringing diversity back into focus.
Org Biomol Chem
August 2008
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UKCB2 1EW.
Through the synthesis of a focused library and SAR investigations, a more potent analogue of gemmacin (discovered in a previous diversity-oriented synthesis (DOS) campaign), gemmacin B, was discovered.
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