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Evaluation of the effects of the third molar on distalization and the effects of attachments on distalization and expansion with clear aligners: Three-dimensional finite element study.
Korean J Orthod
January 2025
Department of Orthodontics, Hacettepe University, Ankara, Türkiye.
Objective: This study aimed to evaluate the effects of attachment design on maxillary molar distalization and simultaneous expansion during distalization, and the influence of third molars on distalization in the clear aligner technique using the finite element method.
Methods: Six models were created to evaluate three different attachment designs on the second molars. Model I: employed a vertical rectangular attachment; Model II: used a vertical rectangular attachment with the presence of the third molar; Model III: used a combined semi-elliptical attachment; and Model IV: featured an opposed semi-elliptical attachment with buccal and palatal components.
Enhancing High-Level Food-Grade Expression of Glutamate Decarboxylase and Its Application in the Production of γ-Aminobutyric Acid.
J Microbiol Biotechnol
December 2024
School of Biotechnology and Key Laboratory of Industrial Biotechnology Ministry of Education, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, P.R. China.
Gamma-aminobutyric acid (GABA), a non-proteinogenic amino acid, exhibits diverse physiological functions and finds extensive applications in food, medicine, and various industries. Glutamate decarboxylase (GAD) can effectively convert L-glutamic acid (L-Glu) or monosodium glutamate (MSG) into GABA. However, the low food-grade expression of GAD has hindered large-scale GABA production.
View Article and Find Full Text PDFCompound heterozygous TMEM67 biallelic variants including a novel frameshift mutation in two Filipino adolescent siblings with Joubert syndrome.
J Neural Transm (Vienna)
January 2025
Section of Adult Neurology, Department of Internal Medicine, Chong Hua Hospital, Fuente, Cebu, Philippines.
Joubert Syndrome (JS) is a congenital cerebellar ataxia typically inherited in an autosomal recessive pattern, although rare X-linked inheritance can occur. It is characterized by hypotonia evolving into ataxia, global developmental delay, oculomotor apraxia, breathing dysregulation, and multiorgan involvement. To date, there are 40 causative genes implicated in JS, all of which encode proteins of the primary cilium.
View Article and Find Full Text PDFAnalytical protocol for measuring micro-molar quantities of sulfur volatile species in experimental high pressure and temperature fluids.
Commun Chem
January 2025
Dipartimento di Scienze Della Terra, Università Degli Studi di Milano, via Mangiagalli 34, I-20133, Milano, Italy.
Validating thermodynamic models is essential in experimental geosciences for exploring increasingly complex systems and developing analytical protocols. However, investigating solid-fluid equilibria in mm-sized experimental capsules poses several challenges, particularly in sulfur-bearing chemical systems. These include maintaining bulk fluid composition and performing quantitative analysis with extremely low amounts of synthesized fluid.
View Article and Find Full Text PDF[Geostatics in impacted mandibular third molar surgury].
Zhonghua Kou Qiang Yi Xue Za Zhi
January 2025
Department of Oral and Maxillofacial Surgery, Shanxi Medical University School and Hospital of Stomatology, Taiyuan 030001, China.
Exploring the application of minimally invasive techniques in the extraction of impacted mandibular third molar (IMTM), to achieve the treatment goal of "less trauma, short time, fast recovery", remains the focus of dentists. For now, the IMTM are mostly extracted in pieces after removing the crown and root resistance by bone removal and tooth segmentation, using 45°reverse-angle high speed turbine, piezosurgery, chisel or other dynamic system. However, There is a lack of principle-level parsing in different provinces and primary hospitals, while experience is still the main factor in avoiding excessive bone removal in complex IMTM extraction, as well as optimizing the specific position and angle of the parting teeth, finding the fulcrum and designing the best dislocation path when there is root resistance.
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