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Parental Factors Associated With Measles-Mumps-Rubella Vaccination in US Children Younger Than 5 Years.
Am J Public Health
January 2025
Eric Geng Zhou is with the Center for Child Health Services Research, Icahn School of Medicine at Mount Sinai, New York, NY. Jonathan Cantor is with RAND, Santa Monica, CA. Autumn Gertz, John S. Brownstein, and Benjamin Rader are with Innovation and Digital Health Accelerator, Boston Children's Hospital, Boston, MA. Brian Elbel is with the Department of Population Health, Grossman School of Medicine, New York University, New York.
To determine the association between parental characteristics and MMR (measles-mumps- rubella) vaccination status of children in the United States. We conducted a cross-sectional study from July 2023 to April 2024 using a digital health survey via OutbreaksNearMe, weighted to target national population characteristics. We analyzed the responses of 19 892 parents of children younger than 5 years to examine the association between self-reported parental characteristics (i.
View Article and Find Full Text PDFSLC35A2 gene product modulates paramyxovirus fusion events during infection.
PLoS Pathog
January 2025
Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Paramyxoviruses are significant human and animal pathogens that include mumps virus (MuV), Newcastle disease virus (NDV) and the murine parainfluenza virus Sendai (SeV). Despite their importance, few host factors implicated in paramyxovirus infection are known. Using a recombinant SeV expressing destabilized eGFP (rSeVCdseGFP) in a loss-of-function CRISPR screen, we identified the CMP-sialic acid transporter (CST) gene SLC35A1 and the UDP-galactose transporter (UGT) gene SLC35A2 as essential for paramyxovirus infection.
View Article and Find Full Text PDFContagion comeback: unravelling the measles outbreak across the USA.
Front Public Health
January 2025
Atish Dipankar University of Science and Technology, Dhaka, Bangladesh.
Measles, a highly contagious respiratory illness caused by the measles virus (MeV), poses significant global and national public health challenges despite advancements in vaccination efforts. Though measles was declared eliminated in the United States in 2000, recent years have seen a resurgence of cases, particularly in under-vaccinated communities. This resurgence is compounded by factors such as vaccine hesitancy, the impact of the COVID-19 pandemic on immunization rates, and international travel introducing new cases from endemic regions.
View Article and Find Full Text PDFTeaching students to effectively evaluate scientific evidence and advocate for research in the context of autism spectrum disorder and the neurodiversity movement.
Dev Biol
March 2025
Department of Biology and Neuroscience Program, Hamline University, St Paul, MN, United States. Electronic address:
Connecting socially relevant topics with biological content can boost student engagement and comprehension. Autism Spectrum Disorder (ASD) is an increasingly prevalent diagnosis with a number of intersecting topic areas between developmental biology and social justice. Here I describe two exercises that I developed to engage students in learning opportunities that link scientific process learning goals with real-world applications.
View Article and Find Full Text PDFEvidence on trends in uptake of childhood vaccines and association with COVID-19 vaccination rates.
Vaccine
January 2025
Pritzker School of Law, Northwestern University, USA.
Importance: Childhood vaccination rates have declined in recent years; there is also concern that resistance to COVID-19 vaccines could spill over to childhood vaccines.
Objectives: To use local-level data to study trends in childhood vaccination rates and heterogeneity in local rates; including how many areas are below herd-immunity thresholds, and assess the association between COVID-19 vaccine hesitancy and childhood vaccination.
Design: We report, for 11 states with available data, vaccination rates for measles, mumps, rubella (MMR), and diphtheria, tetanus, acellular pertussis (DTaP) vaccines, including percentage of schools/counties with rates ≥95 %, 90-95 %, 80-90 %, and < 80 %.
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