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Investigations of Long-Acting Formulations in Children, Adolescents, and Pregnant Women: A Systematic Review.
Pharmaceutics
January 2025
Division of Clinical Pharmacology, Department of Medicine, School of Medicine, The Johns Hopkins University, Baltimore, MD 21287, USA.
Long-acting and extended-release drug delivery strategies have greatly improved treatment for a variety of medical conditions. Special populations, specifically infants, children, young people, and pregnant and postpartum women, could greatly benefit from access to these strategies but are often excluded from clinical trials. We conducted a systematic review of all clinical studies involving the use of a long-acting intramuscular injection or implant in infants, children, young people, and pregnant and postpartum people.
View Article and Find Full Text PDFFraming and Management of Migraines in Women: An Expert Opinion on Challenges, Current Approaches, and Future Multidisciplinary Perspectives.
Healthcare (Basel)
January 2025
Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.
Migraines are a common neurological disorder that significantly impact women, especially during their reproductive years. Hormonal, neurological, and lifestyle factors shape migraine patterns, with fluctuations during menstruation, pregnancy, perimenopause, and menopause influencing migraine prevalence and severity. This expert opinion explores current challenges, therapeutic strategies, and future directions for personalized care, addressing the limited inclusion of women in clinical research across different life stages.
View Article and Find Full Text PDFBeyond individual-level factors that influence family planning uptake among women with diabetes mellitus: a systematic literature review.
BMC Public Health
January 2025
Department of Public Health Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia.
Background: The prevalence of diabetes mellitus among women increased consistently together with the increase in the overall prevalence of diabetes mellitus globally. One of the components in holistic diabetes care among women are preconception interventions. Family planning usage has been one of the components in preconception care among this group of population, especially among women with unoptimised diabetes mellitus, where family planning may allow disease optimisation prior to pregnancy.
View Article and Find Full Text PDFReproduction control in a feral feline population using an anti-GnRH vaccine.
Theriogenology
January 2025
Instituto de Investigaciones en Reproducción Animal, FCV, UNLP, Calle 60 y 118, La Plata, B1900AVW, Buenos Aires, Argentina; Universidad del Chaco Austral, Argentina. Electronic address:
This study aimed to evaluate the use of the Improvac® vaccine to avoid heat and pregnancies in queens and fertility in males during the breeding season. Twenty-eight intact animals were divided into treated males (G1, n = 7), treated females (G2, n = 18), and untreated males (G3, n = 3) that were untamed and could not be captured for immunization. In cats from the G1 group, the testicular volume (337.
View Article and Find Full Text PDFGeographic distribution and demographic factors associated with use of a long-acting reversible contraceptive (LARC) in Ethiopia.
Geospat Health
January 2025
College for Public Health and Social Justice, Saint Louis University, Missouri.
Background: Increasing access to and utilization of long-acting reversible contraceptives (LARC) can prevent unintended pregnancies and reduce unmet need for family planning in Ethiopia However, LARC uptake lags behind less effective contraceptive methods. This study aimed to analyze the geographical distribution and demographic factors associated to LARC uptake.
Methods: The 2019 Performance Monitoring For Action Ethiopia (PMA Ethiopia) survey data was used.
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