Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.4088/jcp.v69n0720b | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Redefining diagnostic lesional status in temporal lobe epilepsy with artificial intelligence.
Brain
January 2025
Department of Neurology, University of South Carolina, Columbia, SC 29203, USA.
Despite decades of advancements in diagnostic MRI, 30-50% of temporal lobe epilepsy (TLE) patients remain categorized as "non-lesional" (i.e., MRI negative or MRI-) based on visual assessment by human experts.
View Article and Find Full Text PDFTracking individual seed fate confirms mainly antagonistic interactions between rodents and European beech.
Biol Lett
January 2025
Department of Ecosystem Management, Climate, and Biodiversity, Institute of Wildlife Biology and Game Management, BOKU - University of Natural Resources and Life Sciences, Vienna, Austria.
Food-hoarding granivores act as both predators and dispersers of plant seeds, resulting in facultative species interactions along a mutualism-antagonism continuum. The position along this continuum is determined by the positive and negative interactions that vary with the ratio between seed availability and animal abundance, particularly for mast-seeding species with interannual variation and spatial synchrony of seed production. Empirical data on the entire fate of seeds up to germination and the influence of rodents on seed survival is rare, resulting in a lack of consensus on their position along the mutualism-antagonism continuum.
View Article and Find Full Text PDFNeeds assessment of people living with cognitive impairment/dementia, a requirement of comprehensive psychogeriatric assessment and person-centered care. Empirical validation of the model in a community study.
Front Psychiatry
December 2024
Psychiatry Department, University of Santiago de Compostela (USC), Santiago de Compostela, A Coruña, Spain.
Introduction: Cognitive impairment and dementia are part of a continuum that progressively leads to functional impairment and dependency. Dementia is a paradigmatic example of chronic and complex psychogeriatric diseases, requiring a comprehensive assessment. The authors underline the importance of implementing a formal assessment of needs (whether met or unmet) as an essential element of comprehensive assessment.
View Article and Find Full Text PDFDynamic self-assembled meso-structures formed across a wide concentration range in aqueous solutions of propranolol hydrochloride.
J Colloid Interface Sci
December 2024
School of Health Sciences, Stopford Building, The University of Manchester, Oxford Road, Manchester M13 9PT, UK.
Hypothesis: Nanoscale characterisation of the self-associated species formed by amphiphilic pharmaceuticals in aqueous solution carries relevance across their entire journey from development through to manufacture - relevant, therefore, not only as regards formulation of the drug products as medicines, but also potentially relevant to their bioavailability, activity, and clinical side effects. Such knowledge and understanding, however, can only be fully secured by applying a range of experimental and theoretical methodologies.
Experiments: Herein, we apply a synergistic combination of solubility, surface tension, SANS, NMR and UV spectroscopic studies, together with MD simulation and QM calculations, to investigate the meso-structures of propranolol hydrochloride aggregates in bulk aqueous solutions, at concentrations spanning 2.
Unsupervised clustering of a deeply phenotyped cohort of adults with idiopathic generalized epilepsy.
Epilepsia
December 2024
Department of Neurology, Odense University Hospital, Odense, Denmark.
Objective: Idiopathic generalized epilepsy (IGE) in adults comprise juvenile myoclonic epilepsy (JME), juvenile absence epilepsy (JAE), and epilepsy with generalized tonic-clonic seizures alone (EGTCS), which are defined by their seizure types but also cover a broad endophenotype of symptoms. Controversy exists on whether adult IGE is a group of distinct diseases or a clinical spectrum of one disease. Here, we used a deeply phenotyped cohort to test the hypothesis that IGE comprises three distinct clinical entities.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!