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Utility of a C-Spirulina Stable Isotope Gastric Emptying Breath Test in Diabetes Mellitus.
Neurogastroenterol Motil
January 2025
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Background: The carbon-13 spirulina gastric emptying breath test (GEBT) is approved to identify delayed, but not accelerated, gastric emptying (GE). We compared the utility of the GEBT to scintigraphy for diagnosing abnormal GE in patients with diabetes mellitus.
Methods: Twenty-eight patients with diabetes ate a 230-kcal test meal labeled with technetium 99 m and C-spirulina, after which 10 scintigraphic images and breath samples (baseline, 15, 30, 45, 60, 90, 120, 150, 180, 210, and 240 min) were collected on 2 occasions 1 week apart.
Overall and Regional Colonic Transit Abnormalities in Elderly Patients with Constipation.
Dig Dis Sci
January 2025
Clinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R.), Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First St. S.W., Charlton Bldg., Rm. 8-110, Rochester, MN, 55905, USA.
Objective: Chronic constipation (CC) more frequently affects the elderly; pelvic floor dysfunction (PFD) may confuse the appraisal of the pathophysiology of CC. The aim was to characterize colonic transit (CT) in elderly with CC with/without PFD.
Design: We conducted retrospective medical records review of 191 patients ≥ 65 years who underwent scintigraphic CT for assessing CC.
Pre-symptomatic scintigraphic and genetic cascade screening in cardiac transthyretin amyloidosis.
Eur J Nucl Med Mol Imaging
November 2024
Jagiellonian University Medical College, Department of Cardiac and Vascular Diseases, Institute of Cardiology, St. John Paul II Hospital, Pradnicka 80, 31-202, Krakow, Poland.
Purpose: While early diagnosis is crucial, as new treatments can significantly slow the progression of the disease, there is growing evidence on the application of novel imaging techniques for detecting transthyretin amyloidosis (ATTR) in pre-symptomatic stages. This study aimed to evaluate the utility of pre-symptomatic scintigraphic imaging cascade screening for early detection of ATTR.
Methods: During the period from 2020 to 2024, we conducted a prospective study that enrolled 100 consecutive adults.
The Utility of Baseline Characteristics and [I]MIBG Cardiac Adrenergic System Scintigraphy in Qualifying Patients with Post-Infarction Heart Failure for Implantable Cardioverter-Defibrillator (ICD) Placement.
J Clin Med
October 2024
Department of Congenital Heart Diseases, National Institute of Cardiology, 04-628 Warsaw, Poland.
Post-infarction heart failure with reduced ejection fraction (HFrEF) patients often face persistent risks of sudden cardiac arrest leading to sudden cardiac death. While implanting a cardioverter-defibrillator (ICD) can enhance prognosis, complications and costs limit its widespread use. Current patient qualification criteria, relying on imperfect parameters, require refinement.
View Article and Find Full Text PDFVascularised and Non-Vascularised Adipofascial Flap Applications in Tissue Trauma with Tendon Injury, Flap Viability and Tendon Healing a Hystological and Scintigraphical Rat Model Study.
Medicina (Kaunas)
October 2024
Faculty Depth of Orthopaedics, Pamukkale University Medicine, Denizli 20160, Turkey.
Article Synopsis
- The study focuses on tendon injuries in complex wounds of the hand and lower extremities, exploring how different types of adipofascial tissue flaps affect healing and functional recovery.
- It compares vascularised versus nonvascularised adipofascial flaps using Wistar Albino rats, assessing healing through scintigraphic evaluations and histopathological analysis.
- Results indicate that vascularised flaps promote faster healing while pedicle-free flaps also aid tendon recovery without complications, providing insights for improving tendon repair techniques in reconstructive surgery.
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